ANTIDOTES

Question 1

Acetaminophen

Answer 1

N-acetylcysteine (replenishes glutathione)

Question 2

AChE inhibitors, organophosphates

Answer 2

Atropine > pralidoxime

Question 3

Amphetamines (basic)

Answer 3

NH4Cl (acidify urine)

Question 4

Antimuscarinic, anticholinergic agents

Answer 4

Physostigmine, control hyperthermia

Question 5

Arsenic

Answer 5

Dimercaprol, succimer

Question 6

Benzodiazepines

Answer 6

Flumazenil

Question 7

β-blockers

Answer 7

Saline, atropine, glucagon

Question 8

Carbon monoxide

Answer 8

100% O2, hyperbaric O2

Question 9

Copper

Answer 9

Penicillamine, trientine

Question 10

Cyanide

Answer 10

Nitrite + thiosulfate, hydroxocobalamin

Question 11

Digitalis (digoxin)

Answer 11

Anti-dig Fab fragments

Question 12

Gold

Answer 12

Penicillamine, dimercaprol (BAL), succimer

Question 13

Heparin

Answer 13

Protamine sulfate

Question 14

Iron

Answer 14

Deferoxamine, deferasirox, deferiprone

Question 15

Lead

Answer 15

EDTA, dimercaprol, succimer, penicillamine

Question 16

Mercury

Answer 16

Dimercaprol, succimer

Question 17

Methanol, ethylene glycol (antifreeze)

Answer 17

Fomepizole > ethanol, dialysis

Question 18

Methemoglobin

Answer 18

Methylene blue, vitamin C

Question 19

Opioids

Answer 19

Naloxone

Question 20

Salicylates

Answer 20

NaHCO3 (alkalinize urine), dialysis

Question 21

TCAs

Answer 21

NaHCO3

Question 22

Warfarin

Answer 22

Vitamin K (delayed effect), fresh frozen plasma
(immediate)