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Pharmacology > Antidotes > Flashcards

Antidotes Flashcards

0
Q

Antidote for salicylates

A

NaHCO3 (alkalinize urine); dialysis

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1
Q

Antidote for acetaminophen

A

N-acetylcysteine - replenishes glutathione

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2
Q

Antidote for amphetamines

A

NH4Cl (acidify urine)

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3
Q

AChE inhibitors, organophosphates

A

Atropine; pralidoxime

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4
Q

Antidote for antimuscarinic/anticholinergic agents

A

Physostigmine salicylate; control hypothermia

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5
Q

Antidote for B-blockers

A

Glucagon

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6
Q

Antidote for digitalis

A

Normalize K+ (digitalis –> hyperkalemia); lidocaine; anti-digitalis Fab fragments; Mg2+

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7
Q

Antidote for iron

A

Deferoxamine; deferasirox

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8
Q

Antidote for lead

A

CaEDTA; dimercaprol; succimer; penicillamine

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9
Q

Antidote for mercury

A

Dimercaprol (BAL); succimer

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10
Q

Antidote for arsenic

A

Dimercaprol (BAL); succimer; penicillamine

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11
Q

Antidote for gold

A

Dimercaprol (BAL); succimer; penicillamine

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12
Q

Antidote for copper

A

Penicillamine

*Wilson’s disease

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13
Q

Antidote for cyanide

A

Nitrite + thiosulfate; hydroxocobalamin

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14
Q

Antidote for methemoglobin

A

Methylene blue; vitamin C

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15
Q

Antidote for carbon monoxide

A

100% O2; hyperbaric O2

16
Q

Antidote for methanol or ethylene glycol (antifreeze)

A

Fomepizole > ethanol; dialysis

17
Q

Antidote for opioids

A

Naloxone/naltrexone

18
Q

Antidote for benzodiazepines

A

Flumazenil

19
Q

Antidote for TCAs

A

NaHCO3 (plasma alkalinization)

20
Q

Antidote for heparin

A

Protamine

21
Q

Antidote for warfarin

A

Vitamin K; fresh frozen plasma

22
Q

Antidote for tPA, streptokinase and urokinase

A

Aminocaproic acid

23
Q

Antidote for theophylline

A

B-blocker

24
Q

What can dimercaprol be used as an antidote for?

A

Lead, mercury, arsenic and gold

25
Q

What can succimer be used as an antidote for?

A

Lead, mercury, arsenic and gold

*same as dimercaprol

26
Q

What can penicillamine be used as an antidote for?

A

Lead, copper, arsenic and gold

Pharmacology (3 decks)

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