Abx To Avoid In Pregnancy Flashcards
0
Q
Effect of sulfonamides
A
Kernicterus - sulfa abx displace bilirubin from albumin; the result is bilirubin-induced brain damage in the fetus
1
Q
Which abx should be avoided in pregnancy?
A
Sulfonamides Aminoglycosides Fluoroquinolones Clarithromycin Chloramphenicol
2
Q
Effect of aminoglycosides
A
Ototoxicity
3
Q
Effect of fluoroquinolones
A
Cartilage damage
3
Q
Effect of tetracyclines
A
Discolored teeth; inhibition of bone growth
5
Q
Effect of clarithromycin
A
Embryotoxicity
6
Q
Effect of chloramphenicol
A
Gray baby syndrome - ashen gray skin color, vomiting, limp baby tone, hypotension, cyanosis, hypothermia, cardiogenic shock
8
Q
What antiviral and antifungal medications are teratogenic?
A
Ribavirin and griseofulvin
