Antidepressants Flashcards by Lindsay Paxton

Q

Phenelzine sulfate

A

MAO Inhibitors Antidepressants

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Q

Isocarboxazid

A

MAO Inhibitors Antidepressants

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Q

Tranylcypromine

A

MAO Inhibitors Antidepressants

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Q

Action of MAO Inhibitors Antidepressants

A

interferes with monoamine oxidase, allowing for increased concentration of neurotransmitters in synaptic space, causing stabilization of mood

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Q

Indications of MAO Inhibitors Antidepressants

A

depression

- chronic pain syndromes

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Q

Side effects of MAO Inhibitors Antidepressants

A

-HTN crisis when taken with foods containing tyramine (cheese, bologna, pepperoni, salami, figs, bananas, raisins, beer, red wine)

Photosensitivity
Weight gain
sexual dysfunction
orthostatic hypotension

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Q

Nursing considerations for MAO Inhibitors Antidepressants

A

not first line for depression
should not be takens with SSRIs
admin anti-HTN meds with caution
avoid other CNS depressants
no alcohol
d/c 10 days before general anesthesia
medications lower seizure threshold
monitor for urinary retention

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Q

Fluoxetine

A

SSRI Selective Reuptake inhibitors Antidepressant

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Q

Citalopram

A

SSRI Selective Reuptake inhibitors Antidepressant

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Q

Escitalopram

A

SSRI Selective Reuptake inhibitors Antidepressant

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Q

Fluvoxamine

A

SSRI Selective Reuptake inhibitors Antidepressant

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Q

Paroxetine

A

SSRI Selective Reuptake inhibitors Antidepressant

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Q

Sertraline

A

SSRI Selective Reuptake inhibitors Antidepressant

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Q

Venlafaxine

A

SNRI Selective Reuptake inhibitors Antidepressant

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Q

Duloxetine

A

SNRI Selective Reuptake inhibitors Antidepressant

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Q

Action of Selective Reuptake inhibitors Antidepressant

A

inhibits CNS neuronal uptake of serotonin

acts as stimulant counteracting depression and increasing motivation

Q

Indications of Selective Reuptake inhibitors Antidepressant

A

depression
OCD
obesity
bulimia

Q

Side effects of Selective Reuptake inhibitors Antidepressant

A

HA
dizziness
nervousness
insomnia
drowsiness
anxiety
tremor
dry mouth
GI upset
sweating
rash
URI
painful menstration
sexual dysfunction
weight gain

Q

Nursing considerations for Selective Reuptake inhibitors Antidepressant

A

take in AM
takes 4 wks to take effect
monitor weight
good mouth care
do not admin with MAOIs
monitor for thrombocytopenia

Q

Amitriptyline

A

Tricyclics Antidepressant

Q

Imipramin

A

Tricyclics Antidepressant

Q

action of Tricyclics Antidepressant

A

inhibits presynaptic reuptake of neurotransmitters norepinephrine and serotonin, anticholinergic action at CNS and peripheral receptors

Q

indications of Tricyclics Antidepressant

A

depression

- obstructive sleep apnea

Q

side effects of Tricyclics Antidepressant

A

sedation
anticholinergic
confusion
photosensitivity
disturbed concentration
orthostatic hypotension
bone marrow depression
urinary retention

nursing considerations of Tricyclics Antidepressant

- 1-3 wks for therapeutic effect, max response 6-9 weeks - daily dose at night to promote sleep and decrease day time side effects - orthostatic hypotension - side effects will decrease over time - sugarless lozenge for dry mouth - do not stop abruptly - avoid alcohol - avoid exposure to sun, wear sunscreen - OA: strong anticholinergic and sedation effects

Bupropion

Heterocyclics Antidepressants

Trazodone

Heterocyclics Antidepressants

action of Heterocyclics Antidepressants

does not inhibit MAO, has some anticholinergic and sedative effects, alters effects of serotonin on CNS

indications for Heterocyclics Antidepressants

tx of depression and smoking cessation

side effects of Heterocyclics Antidepressants

- dry mouth - nausea - bupropion - insomnia and agitation - trazodone - sedation, orthostatic hypotension

nursing considerations of Heterocyclics Antidepressants

- may require gradual reduction before stopping | - avoid alcohol, other CNS depressants for up to 1 week after end of therapy