Antidepressants Flashcards
1
Q
TCA MOA?
A
Inhibit uptake: NE, 5HT
Block M, alpha, histamine receptors
2
Q
TCA drug names? (4)
A
Amitriptyline
Imipramine
Nortriptyline
Desipramine
3
Q
TCA common s/e? (7)
A
Sedation Tachy/palp Ortho hypoTN Constipation Urinary retention Weight gain Sex dysfxn
4
Q
TCA bad s/e? (4)
A
Seizures
SIADH (hypoNa+)
Torsades in OD
Serotonin synd
5
Q
TCA uses? (3)
A
Depression
Panic
Chronic pain/Fibro
6
Q
SSRI drug names? (5)
A
Fluoxetine/Prozac Paroxetine/Paxil Sertraline/Zoloft Citalopram/Celexa Escitalopram/Lexapro
7
Q
SSRI uses?
A
Depression (class is DOC) Panic OCD (Paxil DOC) Social anxiety (Paxil DOC) Bulimia EtOH
8
Q
SSRI s/e? (5)
A
N/D/C Anxiety Insomnia (flu, ser) Sedation (pax) Sex dysfxn
9
Q
SSRI bad s/e? (3)
A
Serotonin synd (esp MAOI, St John's) Drug interactions (anticonvulsants, warfarin, b-block) SIADH
10
Q
SNRI drug names? (3)
A
Venlafaxine/Effexor
Duloxetine/Cymbalta
Desvenlafaxine/Pristiq
11
Q
SNRI uses? (5)
A
Depression Panic/GAD/PTSD DM neuro pain Fibro Hot flashes
12
Q
SNRI s/e? (5)
A
Same as SSRI Anorexia Sweating Dizziness HTN
13
Q
Duloxetine/Cymbalta contraindicated for who?
A
Narrow-angle glaucoma
14
Q
Best SSRI for EtOHics?
A
Paxil (withstands reduced effectiveness caused by EtOH)
15
Q
Bupropion MOA?
A
Inhib DA/NE re-uptake