Anticonvulsant Drugs (Neuro Drugs)

Question 1

T/F: Pentobarbital is the first choice for seizures control in dogs due to its low cost and high success rate

Answer 1

F

Phenobarbital
Pentobarbital is used as injectable anesthetic that is typically used in overdose of euthanasia

Question 2

T/F: SSRIs (Selective Serotonin-Reuptake Inhibitors) such as sertraline may cause paradoxical excitability and/or disinhibition of aggression in some patients.

Answer 2

False

Benzodiazepines do this.

Question 3

What does phenobarb do to the GABA receptor?

Answer 3

enhances its effect which makes it harder for the cell to depolarize

Question 4

What are the adverse effects of Phenobarb?

Answer 4

Polyuria
Polydipsia
Polyphagia

Question 5

What two blood values may be increased if on phenobarb, and is it considered normal?

Answer 5

ALP & ALT

Yes- this is normal because phenobarb makes the body produce more of those two values

Question 6

What is the emergency anticonvulsant?

Answer 6

Diazepam

Question 7

How is diazepam given? Why?

Answer 7

IV because there is a first pass effect if given PO

Question 8

What 2 bromides can be used for seizure activity? How are they used?

Answer 8

KBr & NaBr

Use in conjunction with phenobarb for increased seizure control