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ACLS > Anticoagulants, antiplatelets, and thrombolytics > Flashcards

Anticoagulants, antiplatelets, and thrombolytics Flashcards

1
Q

Is heparin an anticoagulant or antiplatelet?

A

Anticoagulant

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2
Q

Is Ticagrelor (brilinta) an anticoagulant or antiplatelet?

A

Antiplatelet

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3
Q

Is Bivalirudin an anticoagulant or an antiplatelet?

A

Anticoagulant

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4
Q

Is Dabigatran (Pradaxa) an anticoagulant or an antiplatelet?

A

Anticoagulant

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5
Q

Is warfarin (coumadin) an anticoagulant or an antiplatelet?

A

Anticoagulant

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6
Q

Is Clopidogrel (plavix) an anticoagulant or an antiplatelet?

A

Antiplatelet

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7
Q

Is aggrastat an anticoagulant or an antiplatelet?

A

Antiplatelet

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8
Q

Is Rivaroxaban (Xarelto) an anticoagulant or an antiplatelet?

A

Anticoagulant

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9
Q

Is apixaban (eliquis) an anticoagulant or an antiplatelet?

A

Anticoagulant

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10
Q

Is low molecular weight heparin an anticoagulant or an antiplatelet?

A

Anticoagulant

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11
Q

What is intravenous glycoprotein IIb/IIa inhibitor/ antiplatelet called?

A

Tirofiban

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12
Q

What is the loading dose for tirofiban?

A

25mcg/kg over five minutes or less

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13
Q

What is the Intravenous anticoagulant/direct thrombin inhibitor. The MAG states it is used in cath lab and during a CABG surgery.

A

Bivalirudin

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14
Q

What are the complications for thrombolytic medications?

A
  • bleeding
  • reperfusion dysrhythmias
  • stroke
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15
Q

What are the indications for heparin sodium?

A
  1. prevent clot formation
  2. prevent venous thromboembolism
  3. early treatment of unstable angina, ACS, and acute MI
  4. stroke
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16
Q

What are heparin sodium’s actions?

A

Indirect thrombin inhibitor, does not lyse clots.

17
Q

What are the contraindications when using heparin sodium along with other anticoagulants?

A
  • doesn’t mix well with other medications or herbal supplements (garlic).
  • aneurysm
  • coagulopathy
  • hepatic disease
  • PUD
  • pregnancy
18
Q

What are the complications if protamine sulfate is given too fast?

A
  • hypotension
  • bleeding
  • dyspnea
  • sinus bradycardia
19
Q

What are the two direct thrombin inhibitors?

A

Tenecteplase (IV) and altepase (oral)

20
Q

What are the actions of tenecteplase?

A

Bind to fibrin and convert plasminogen to plasmin

21
Q

What are the actions of warfarin?

A

Anticoagulant and vitamin K antagonist

22
Q

What is the classification of argatroban?

A

Anticoagulant (direct thrombin inhibitor)

23
Q

Why might we give argatroban over heparin sodium?

A

When there are hepatic issues.

24
Q

What are the indications for using Rivaroxaban (Xarelto) and apixaban (eloquis)?

A
  • Non vascular atrial fibrillation
  • PE treatment
  • DVT prophylaxis
25
Q

What are the adverse side effects from clopidogrel (plavix)?

A
  • bleeding
  • pruritis
  • epistaxis
  • hematoma
  • TTP
26
Q

What is the antidote for heparin sodium? (LMWH)

A

Protamine sulfate

27
Q

What is the antidote for warfarin? (Coumadin)

A

K Central

28
Q

What is the antidote for Dabigatran? (Pradaxa)

A

Praxbind

29
Q

What is the antidote for Rivaroxaban (Xarelto) and Apixaban (eloquis)?

A

Andexxa

ACLS (7 decks)

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