Anticoagulants and Antiplatelet Drugs Flashcards
if a patient is taking DOAC and requires a low risk dental procedure how should you treat them
treat without interrupting their anticoagulant medication and treat early in the day
if a patient is taking apixaban or dabigatran and requires a dental procedure with a higher risk of bleeding what should you tell them
miss their morning dose
if a patient is taking rivaroxaban or edoxaban and requires a high bleeding risk dental procedure what should you tell them
delay their morning dose
what is the function of warfarin
a vitimin K agonist
how should you treat a patient who is taking warfarin with an INR below 4
treat without interrupting their anticoagulant medication
if a patient who is taking warfarin is going to undergo a dental treatment likely to cause bleeding what should you do
ensure the INR has been checked - ideally no more than 24 hours before
what should you do for a patient taking warfarin if their INR is above 4
delay treatment until the INR is reduced
how should you treat a patient taking a prophylactic (low) dose of a low molecular weight heparin - injectable
treat without interrupting their anticoagulant medication
what is the guidance for treating a patient on an antiplatelet drug
treat without interrupting their antiplatelet medication
how long would you expect a patient taking an antiplatelet to bleed after a procedure
up to an hour
what is involved in platelet formation
platelets become activated when there is damage to blood vessels causing them to adhere to one another and to the damaged blood vessel endothelium
what type of haemostasis are platelets involved in
primary
what is the action of coagulation
a cascade of reactions initiates that converts inactive coagulation factors to active forms which causes production of fibrin
what is the action of fibrin
stabilises the primary platelet plug by cross linking the platelets to each other and to the damaged blood vessel wall to prevent further blood loss
what type of haemostasis is coagulation
secondary haemostasis
how do antiplatelet drugs work
interfere with platelet aggregation by reversibly or irreversibly inhibiting various steps in the platelet activation required for primary haemostasis