Anticoagulants: 3 Questions Flashcards

1
Q

What is an emboli to the brain?

A

Stroke: Caused by a blood clot that forms elsewhere in the body and travels through the bloodstream to the brain.

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2
Q

What is an emboli to the lung ?

A

Pulmonary Embolism: a sudden blockage in the pulmonary arteries, the blood vessels that send blood to your lungs.

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3
Q

What is an emboli to the vein in the leg?

A

Deep Vein Thrombosis “DVT”: a medical condition that occurs when a blood clot forms in a deep vein.

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4
Q

What does anticoagulants do?

A

Prevention of new clots and the growth of existing clots. DO NOT DISSOLVE CLOTS. Thins the blood to make the river flow.

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5
Q

What is the two Anticoagulant drugs?

A

Heparin and Warfarin (Coumadin)

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6
Q

Which medication is given IV?

A

Heparin

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7
Q

Which medication is given PO?

A

Warfarin

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8
Q

Which medication is given SC?

A

LMWH: : Lovenox

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9
Q

What is the reason to give Heparin?

A

-For emergency needs such as stroke, PE, and massive DVT
- Prevent clots during specific surgeries
-Post of blood clots: Venous Thrombosis
-Treat DIC

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10
Q

What should you do as a nurse before administering Heparin?

A

Double check the doses with another nurse

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11
Q

What is the antidote for Heparin?

A

Protamine Sulfate (IV) 1mg

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12
Q

What labs should you do for Heparin ?

A

APTT (Activated Prothrombin Time)

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13
Q

What cautions should you indicate before administering Heparin?

A

Hemophilia, Peptic Ulcers, decrease puncture.

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14
Q

When should LMWH (Lovenox) be given ?

A

Given to patients at high risk for blood clots (Immobile, elderly, post-op)

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15
Q

What does Lovenox cause ?

A

Bruising

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16
Q

Can Lovenox be used as an Anticoagulation ‘Bridge’ before surgery?

A

Yes

17
Q

What are the contraindications for Heparin?

A

thrombocytopenia (low platelets) and uncontrolled bleeding

18
Q

When should you stop Heparin?

A

if platelets less than 100,000/mm3

19
Q

What should you do before administering Heparin IV?

A

Test Dose for allergy

20
Q

What is the MOA of Warfarin?

A

Antagonizes Vitamin K which inhibits factor 7,9,10 and prothrombin.

21
Q

What does Warfarin treat?

A

Treatment of Venous thrombosis, PE, MI, TIA, DVT, atrial fibrillation, and prosthetic heart valves.

22
Q

Can you start Heparin and Warfarin Together?

A

Yes because the onsets are different. Heparin is quicker than Warfarin

23
Q

How long does the therapeutic effect take place for warfarin ?

A

Several Days

24
Q

What labs do you monitor for Warfarin?

A

PT and INR

25
Q

What is normal INR?

A

1-1.5

26
Q

What is INR for MI, AFIB, PE, and Venous thrombosis?

A

2-3

27
Q

What is INR for mechanical heart valves, reoccurring systemic embolism
Green leafy vegetables?

A

2.5-3.5

28
Q

What adverse effect is associated with Warfarin ?

A

Purple toes syndrome

29
Q

What is normal PT?

A

18-24 seconds, over 24 = blood is to thin.

30
Q

What does INR indicate?

A

How long a patient needs for blood to clot. Warfarin 2x

31
Q

What is the antidote for Warfarin?

A

Vitamin K(Phytonadione):
2.5mg PO, 0.5 to 1 mg IV

32
Q

Does Warfarin have many interactions ?

A

Yes

33
Q

Should you take Herbal products while on Warfarin?

A

no

34
Q

What should patients eat to thicken the blood ?

A

Greens (Vitamin K)

35
Q

During bleeding assessment look for ?

A

visual assessment- blood you can see
Guaiac Fecal Occult stool- blood you cannot see.