Anticoagulants

Question 1

Anticoagulants General MOA

Answer 1

Prevents clot extension and formation (does not dissolve clots) by interrupting coagulation pathways.

Question 2

Anticoagulants Indications

Answer 2

Prevents DVT after surgery or with prolonged bed rest. Clotting disorder?? - look this up

Question 3

Anticoagulants Contraindications

Answer 3

Coagulation disorders, ulcer disease, malignancy, recent surgery, active bleeding

Question 4

Anticoagulants Assessment

Answer 4

Signs of bleeding or hemorhage,unusual bruising. Evidence of additional or increasing thrombosis

Question 5

Anticoagulants Lab Tests

Answer 5

INR, PTT, PT (Insert values that we are looking for)

Question 6

Anticoagulants Antidotes

Answer 6

Heparin - Protamine Sulfate
Warfarin - Vitamin K

Question 7

Anticoagulants Pt Education

Answer 7

• Avoid activities that can lead to injury
• soft bristle toothbrush, electric razor
• report unusual bleeding or bruising
• ## don’t take OTC meds unless you talk to health care provider first

Question 8

Heparin MOA

Answer 8

Heparin inhibits conversion of prothrombin to thrombin by inhibiting Xa. This stops conversion of fibrinogen to fibrin.

Question 9

Warfarin MOA

Answer 9

Interferes with hepatic synthesis of Vitamin K dependent clotting factors (II,VII,IX,X).