Antibodies testing Flashcards
1
Q
Antibodies to tests for Anti-phospholipid Syndrome (2)
A
- Lupus anticoagulant (LA)
- Anti-cardiolipin antibodies (aCL)
2
Q
Antibody to test for RA
A
Anti-cyclic-citrullinated-peptide antibodies
3
Q
Antibody to test for SLE
A
Anti-double stranded DNA
4
Q
(2) antibodies to test for polymyositis
A
- Anti-Jo-1
- Anti-Mi-2
5
Q
(2) antibodies to test for Sjogren’s syndrome
A
- anti-Ro
- anti - La
6
Q
Antibody to test for granulomatosis with polyangiitis (Wegener’s granulomatosis)
A
- cANCA positive in > 90%
- pANCA positive in 25%
7
Q
Antibody for Churg-Strauss Syndrome
A
pANCA
8
Q
What does Anti-Jo1 detect? (2)
A
Polymyositis and dermatomyositis
9
Q
Examples of conditions where pANCA can be found (3)
A
- microscopic polyangiitis
- eosinophilic granulomatosis with polyangiitis (aka Churg Strauss)
- Goodpasture syndrome
10
Q
Examples of conditions where cANCA can be found (2)
A
- granulomatosis with polyangiitis (previously known as Wegener’s)
- microscopic polyangiitis
11
Q
Antibody tested for in rheumatoid arthritis
A
Anti-CCP
12
Q
What disease do we test for using Anti-Scl-70?
A
Diffuse Systemic Sclerosis
13
Q
Anti Mitochondrial Antibody (AMA) in which disease?
A
Primary Biliary Cirrhosis (PBC)
