antibodies Flashcards
what are antibodies also known as
immunoglobulins
they are globular glycoproteins
where are antibodies produced
by b lymphocytes in response to infection
decribre antibody structure
[think Y shape]
constat region
variable region
2 identical antigen binding site
heavy chain
light chain
hinge region
disulphide bond between chains
what determines shape variable region
order amino acids
what do antibodies do
cause agglutination of bacteria so less spread
block binding sites on pathogen
labels to identify antigens for phagocytes
antitoxins
attach to flagella so less active and easier engulf by phagocytes
what are the heavy and light chains
polypeptides
describe secondary response
reinfect same infection
rapid and stronger response
memory cells
describe primary response
infection
lag phase
antibodies produced
antibody level rises
infection dealt
antibodies die