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اميون > Antibodeis > Flashcards

Antibodeis Flashcards

1
Q

Ab isotype is different in ?

A

Heavy chain

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2
Q

J chain is fond in ?

A

IgM and IgA

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3
Q

What is the type is used for paternity testing ?

A

Allotypes

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4
Q

What is the It is the major Ig in normal
human serum (70-75%) of
the total Ig pool ?

A

IgG

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5
Q

IgG consists of a ?

A

monomeric unit

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6
Q

What is the main antibody in the secondary response?

A

IgG

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7
Q

What is the type of complement in the IgG ?

A

Classical pathway

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8
Q

What is the function of IgG ?

A

1- classical pathway activation
2- placenta transfer ( passive immunity)
3- Neutralization of toxins
4- Opsonization
5- 2ndry IR (Memory cell receptor)

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9
Q

What is the main antibody in the primary immune response

A

IgM

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10
Q

What is the antibodies used in classical pathway ?

A

IgM and IgG

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11
Q

IgM don’t passive placenta so it is used to diagnosis of ?

A

1- Intrauterine fetal infection
2- re correct infevtion

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12
Q

What is the antibody aginst the blood group ?

A

IgM

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13
Q

What is the function of IgM ? ( BCR I )

A

1- BCR
2- Baby intrauterine infection
3- Blood groups (anti-A & anti-B)
4- Bacteremia
5- CLassical pathway activation
6- Recent infection
7- 1ry IR
8- Thymus Independent Ags

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14
Q

What is the antibody is the Mucous Membranes & Mucus ?

A

IgA

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15
Q

What is the antibody fond in the Brest milk ?

A

IgA

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16
Q

can be inactivated by an IgA
protease produced by gonococci,
pneumococci and H. influenza?

A

IgA1

17
Q

is more important in mucosal
immunity against such pathogens ?

A

IgA2

18
Q

What is the function of IgA ? ( GPA )

A

1- Gate keeper
2- Prevents Adherence & Attachment of organisms
3- Prevents Autoimmune diseases
4- Prevents Allergy

19
Q

Smooth muscle contraction, increased
vascular permeability, irritation ?

A

Histamine

20
Q

Smooth muscle contraction, inflammation, irritation ?

A

Kinins

21
Q

Damage tissues and activate complement ?

A

Proteases

22
Q

Slow prolonged smooth muscle contraction ?

A

Leukotrienes

23
Q

Systemic allergy from type I hypersensitivity ?

A

anaphylactic shock

24
Q

Hypersensitivity reaction in respiratory tract from type I hypersensitivity ?

A

allergic rhinitis， allergic asthma

25
Q

Hypersensitivity reaction in gastrointestinal tract from type I hypersensitivity ?

A

Food allergies

26
Q

hypersensitivity reaction in skin from type I hypersensitivity ?

A

atopic dermatitis, urticaria

27
Q

What is the function of IgE ? ( 3 HE )

A

1- Homocytotropic
2- Helminthis (ADCC) (Hygeine)
3- Hypersensitivty reaction type 1

اميون (4 decks)

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