المحاضرة الحمراء Flashcards
How can the immune system differentiates
between different antigens?
By antigen receptor
Epitopes bind to ?
TCR or BCR
What is the smallest AgDIunit f i
biochemical unit of an Ag that is capable of eliciting an immune response ?
Epitope
What is the APC ?
1- Macrophages
2- dendritic cells
3- B cells
APC They express ?
MHC class II
What is the main APC ?
Dendritic cells
Extracellular antigens Processed by ?
APC
Intracellular antigens Processed by ?
host cell
MHC class II processing pathway ?
Externally
MHC class I processing pathway ?
Internally
CD4+ TH cells are ?
MHC II
CD8+ Tc cells are ?
MHC I
B 7 bind with ?
CD28
Thymus- dependent antigens induce ?
IgM production as well as production of other Ig isotypes.
Thymus- independent insideBm of
antigens “TI antigens” induce ?
IgM production only
Are the most potent immunogens?
Proteins
Weak immunogenic to high immunogenic ?
Adjuvant
The 1st adjuvant preparation used was ?
Al(OH)3