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Antimicrobials > Antibiotics III- Clinical Application > Flashcards

Antibiotics III- Clinical Application Flashcards

1
Q

Uncomplicated Skin and soft tissue infections (2)

If allergic to first two then give (2)

A
  1. Penicillins (ampicillin)
  2. Cephalexin
  3. if allergic– Vancomycin or Clindamycin
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2
Q

Complicated Skin and Soft tissue infection

A

*Pencillin + lactamase inhibitor

Ticarcillin + calvulanate acid

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3
Q

MRSA

A

Vancomycin
Daptomycin
Linezolid

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4
Q

Osteomyelitis

A

Vancomycin or Cephalosporins (ceftriaxone or cefepime)

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5
Q

Surgical infections

A

*Penicillin + lactamase inhibitor

Ticarcillin + calvulanate acid

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6
Q

Septic Arthritis

Empiric and MRSA

A

Empiric: Ceftriaxone
MRSA: V, L, D

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7
Q

Prosthetic Joint

A

Rifampin

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8
Q

Acute sinusitis

A

Penicillin + lactamase inhibitor

*AMOXICILLIN + CLAVULANATE

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9
Q

Pharyngitis

A

PENICILLIN or AMOXICILLIN

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10
Q

Community acquired bacterial pneumonia- ambulatory

A

Macrolide (erythromycin, azithromycin, clarithromycin)

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11
Q

Community acquired bacterial pneumonia- hospitalization

A

B-lactam + macrolide

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12
Q

Community acquired bacterial pneumonia- MRSA

A

Vancomycin, linezolid (not sure why but daptomycin is not listed in ppt)

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13
Q

Hospital or ventilator acquired bacterial pneumonia- Empiric

MRSA

A

Empiric: Ceftriaxone
MRSA: V + L, no D…that’s too bad…D is good sometimes

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14
Q

Uncomplicated UTI- Cystitis

A

TMP-SMX

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15
Q

Uncomplicated UTI- Pyelonephritis

A

TMP-SMX or Fluoroquinolone

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16
Q

Complicated UTI

A

TMP-SMX or Fluoroquinolone

17
Q

Prostatitis

A

TMP-SMX or Fluoroquinolone

18
Q

Intra-abdominal Infections

A

Ticarcillin + calvulanate

19
Q

C. Diff infection

A

Metronidazole (moderate)

Vancomycin (severe)

20
Q

Community-acquired bacterial meningitis

A

Ceftriaxone or cefotaxime (3rd generation)

+ Vancomycin

21
Q

Neonatal meningitis

A

Ampicilin + cephalosporin +/- gentamicin

22
Q

Sepsis

A

3rd or 4th generation cephalosporin (*Cefepime) + vancomycin

23
Q

Endocarditis

A

Ceftriaxone + vancomycin

24
Q

Fever and neutropenia (empiric)

A

Ciprofloxacin + Amoxicillin/calvulanate

25
Q

MDR Enterococci

A

Linezolid
Daptomycin
Tigecycline

26
Q

MDR Gram negative bacteria

Expressing b-lactamase:

A

Imipenem or meropenem

27
Q

MDR Gram negative bacteria

Expressing carbapenemases

A

Polymyxin B or Tigecycline

Antimicrobials (5 decks)

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