Antibiotics- Against Pseudomonas

Question 1

Beta- lactam drug against Pseudomonas

Answer 1

Piperacillin-Tazobactam

Question 2

Cephalosporins against Pseudomonas ? Generation?

Answer 2

Ceftazidime(3rd), Cefepime(4th)

Question 3

Carbapenems against Pseudomonas? Reserved for?

Answer 3

Meropenem, Imipenem

• For resistant infections

Question 4

Monobactam against Pseudomonas? Coverage

Answer 4

Aztreonam, gram negative coverage

Question 5

Fluroquinolones against Pseudomonas ? Strongest

Answer 5

Ciprofloxacin (strongest), Levofloxacin

Question 6

Aminoglycosides drug against Pseudomonas

Answer 6

GENTAMYCIN and Tobramycin

Synergistic with beta lactams : Piperacillin tazobactam with tobramycin

Question 7

LAST resort option due to toxicity, for multi- drug resistant strains polyclinic E

Answer 7

Colistin

Question 8

Pseudomonas aeruginosa is a

Answer 8

Gram-negative

Question 9

Common infections

Answer 9

Pneumonia (especially ventilator-
associated),
UTIs,
bacteremia,
skin
soft tissue infections, and burns.

Question 10

Resistance

Answer 10

Notoriously resistant to many antibiotics due to efflux pumps, porin channel mutations, and biofilm production.