Antibiotics

Question 1

Exacerbation of chronic bronchitis

Answer 1

amoxicillin or tetracycline or clarithromycin

Question 2

Uncomplicated community acquired pneumonia

Answer 2

amoxicillin or clarithromycin or doxycycline

flucloxacillin if staph suspected

Question 3

Atypical pneumonia

Answer 3

clarithromycin

Question 4

Hospital acquired pneumonia

Answer 4

• within 5 days of admission: co-amoxiclav or cefuroxime

- more than 5 days after admission: piperacillin with tazobactam or broad spectrum cephalosporin or quinolone

Question 5

Lower UTI

Answer 5

trimethoprim or nitrofurantoin

alt. amoxicillin or cephalosporin

Question 6

Acute pyelonephritis

Answer 6

broad spectrum cephalosporin or quinolone

Question 7

Acute prostatitis

Answer 7

quinolone or trimethoprim

Question 8

Impetigo

Answer 8

topical hydrogen peroxide, oral flucloxacillin or erythromycin if widespread

Question 9

Cellulitis

Answer 9

flucloxacillin

penicillin allergic: clarithromycin, erythromycin or doxycycline

Question 10

Cellulitis near eyes or nose

Answer 10

co-amoxiclav

clarithromycin and metronidazole if penicillin allergic

Question 11

Erysipelas

Answer 11

flucloxacillin

penicillin allergic: clarithromycin, erythromycin or doxycycline

Question 12

Animal or human bite

Answer 12

-co-amoxiclav

doxycycline and metronidazole if allergic

Question 13

Mastitis during breast-feeding

Answer 13

flucloxacillin

Question 14

Throat infections

Answer 14

phenoxymethylpenicillin

erythromycin

Question 15

Sinusitis

Answer 15

phenoxymethylpenicillin

Question 16

Otitis media

Answer 16

amoxicillin

erythromycin

Question 17

Otitis externa

Answer 17

flucloxacillin

erythromycin

Question 18

Periapical or periodontal abscess

Answer 18

amoxicillin

Question 19

Gingivitis: acute necrotising ulcerative

Answer 19

metronidazole

Question 20

Gonorrhoea

Answer 20

IM ceftriaxone

Question 21

Chlamydia

Answer 21

doxycycline or azithromycin

Question 22

PID

Answer 22

oral ofloxacin + oral metronidazole or IM ceftriaxone + oral doxycycline + oral metronidazole

Question 23

Syphilis

Answer 23

benzathine benxylpenicillin or doxycycline or erythromycin

Question 24

Bacterial vaginosis

Answer 24

oral/topical metronidazole or topical clindamycin

Question 25

C diff

Answer 25

first episode: metronidazole

second: vancomycin

Question 26

Campylobacter enteritis

Answer 26

clarithromycin

Question 27

Salmonella (non-typhoid)

Answer 27

ciprofloxacin

Question 28

Shigellosis

Answer 28

ciprofloxacin

Question 29

Metronidazole ADR

Answer 29

disulfiram like reaction with alcohol

Question 30

Rifampicin ADR

Answer 30

• potent CYP450 liver enzyme inducer
• hepatitis
• orange secretions
• flu-like symptoms

Question 31

Sulfonamide ADR

Answer 31

• hyperkalaemia
• headache
• rash (Steven Johnson syndrome)

Question 32

Tetracycline ADR

Answer 32

• teeth discolouration
• photosensitivity
• angioedema
• black hairy tongue

Question 33

Trimethoprim ADR

Answer 33

• myelosuppression
• transient rise in creatinine
• teratogenic risk in first trimester

Question 34

Vancomycin ADR

Answer 34

• nephrotoxicity
• ototoxicity
• thrombophlebitis
• red man syndrome (on rapid infusion)

Question 35

Chloroquine CONTRA

Answer 35

epilepsy

Question 36

Doxycycline ADR

Answer 36

• oesophagitis

- photosensitivity