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Sepsis > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

When administering antibiotics how should this be managed and decided on?

A

Start smart then focus

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2
Q

What does start smart then focus entail?

A

Think ‘Do they have an infection and if so will antibiotics help?’
Pick right empiric antibiotics for situation.
Focus antibiotics for organism once IDed
Step down from IV to oral ASAP

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3
Q

What are the 4C antibiotics?

A

Co-Amoxiclav
Ciprofloxacin- All ending in ‘floxacin’
Clindamycin
Cephalosporin

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4
Q

Why should 4C antibiotics not be used?

A

Due to the risk of C. Diff infections

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5
Q

What three antibiotics are generally used in empiric treatment and what do they cover?

A

Amoxicillin- Gram +ive
Gentamicin- Gram -ive
Metronidazole- Anaerobs

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6
Q

Can you drink alcohol with metronidazole?

A

No

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7
Q

Why can’t you mix metronidazole and gentamicin in saline?

A

Will precipitate out

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8
Q

What is a side effect of giving vancomycin too fast?

A

Red man syndrome

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9
Q

What 11 antibiotics and classes of antibiotics do we need to know?

A 
Penicillins
Flucloxacillin + Co-amoxiclav 
Quinolones
Cephalosporins
Macrolides
Gentamicin
Vancomycine 
Tetracyclins
Co-trimoxazole
Carbapenems
Metronidazole
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10
Q

Give some side effects of penicillins

A

Hypersensitivity/allergy

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11
Q

Give some side effects of Flucloxacillin + Co-amoxiclav

A

Jaundice

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12
Q

Give some side effect of quinolones

A

Convulsions
Tendonitis
Prolonged QT interval
AAA

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13
Q

Give some side effects of macrolides

A

Prolonged QU interval
Hepatitis
GI upset

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14
Q

Give some side affects of gentamicin

A

Ototoxicity

Nephrotoxicity

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15
Q

Give some side effects of tetracyclins

A

Teeth staining
Heptaotoxicity
Photosensitivity

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16
Q

Give some side effects of co-trimoxazole

A

Stevens-Johnson syndrome (similar to TEN)

17
Q

Give some examples of quinolones

A

Anything ending in ‘floxacin’

Ciprofloxacin

18
Q

Give some examples of macrolides

A

Azithromycin

Erythromycin

19
Q

Give some examples of tetracyclins

A

All end in ‘cycline’

Tetracycline

20
Q

Give some examples of carbapenems

A

Rifampicin

21
Q

What are penicillin G/Benzylpenicillin?

A

IV penicillin

22
Q

What should you do after giving gentamicin for 72h?

A

Test kidney function

23
Q

How many people actually have a beta-lactam allergy?

A

<0.05%

24
Q

If you are allergic to beta-lactams what antibiotics does this include?

A

Penicillins
Cephalosporins
Carbapenems

25
Q

What is clarithromycin used for?

A

Atypical pneumonia

26
Q

What is levofloxacin used for?

A

Resp quinolone

27
Q

Is vancomycin orally absorbed?

A

No

28
Q

Can you give rifampicin on its own?

A

No

Sepsis (3 decks)

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