Antibiotics

Question 1

What drugs are bactericidal?

Answer 1

• beta lactams
• vancomycin
• TB drugs are mix
• quinolones
• aminoglycosides

Question 2

What drugs are bacteriostatic?

Answer 2

1. Antimetabolites
2. Rifampicin
3. Tetracyclines
4. Chloramphenicol
5. Macrolides

Question 3

What are quinolone used for?

Answer 3

1. Urinary tract infection
2. Acute diarrhoea caused by e.coli, shigella sp, salmonella sp
3. H. Influenza

Question 4

What are amino-glycosides used for?

Answer 4

1. Mycoplasma

2. Limited to life threatening situations involving infection with gram -ve

Question 5

How does chloramphenicol work?

Answer 5

Binds to 50S subunit and stops transpeptidation

• used in life threatening respiratory tract, ear, sinuses, meninges