Antibiotics Flashcards
Define “antibiotic”
Chemicals killing/inhibiting the growth of pathogens
What are the 2 types of antibiotic?
- Bacteriostatic
- Bacteriocidal
What do bacteriocidal antibiotics do?
Kill bacteria
How do bacteriocidal antibiotics kill bacteria? 3
- Inhibit enzymes needed to make chemical bonds in bacterial cell walls - causing a weak wall
- Can’t take pressure of osmosis: cell lysis
- Also causes cell membrane disruption by changing permeability of it - causing cell lysis
What do bacteriostatic antibiotics do?
- Prevent bacteria reproducing
- Immune system then destroys bacteria
How do bacteriostatic bacteria prevent bacteria reproducing? 6
- Bind to bacterial ribosomes
- So no translation
- Can’t make proteins
- Can’t make enzymes
- Can’t carry out metabolic processes
- No cell division/growth
Why do antibiotics only work on bacteria?
Antibiotics designed to target bacterial cells by targeting specific differences between eukaryotic cells and prokaryotic cells
What differences in bacteria do antibiotics target?
- Peptidoglycan cell walls [inhibit cell wall formation]
- Smaller ribosomes [so inhibit these ribosomes]
- Different enzymes
Why don’t antibiotics work on viruses?
Viruses don’t have their own enzymes and ribosomes so antibiotics can’t target/affect these