Antibiotics

Question 1

Name the 4 main types of antimicrobials.

Answer 1

antibacterials, antifungals, antivirals and antiprotozoals

Question 2

What is antibacterial class based on?

Answer 2

chemical structure

Question 3

What is the difference between bactericidal or bacteriostatic agents?

Answer 3

bactericidal : kill bacteria

bacteriostatic : inhibit growth or reproduction

Question 4

Name 6 ideal features of antimicrobial agents.

Answer 4

1- selectively toxic
2- few adverse effects
3- reach site of infection
4- oral/IV formulation
5- long 1/2 life (infrequent dosing)
6- no interference with other drugs

Question 5

Which 2 bacterial classes target cell wall synthesis?

Answer 5

1. beta-lactams (inc. penicillin, flucloxacillin, cefuroxime)
2. glycopeptides (inc. vancomycin)

Question 6

Which bacterial class targets cell membrane function?

Answer 6

polymixins (e.g. colistin)

Question 7

Which 3 bacterial classes target protein synthesis?

Answer 7

1. tetracyclines
2. aminoglycosides
3. macrolides

Question 8

Which bacterial class targets nucleic acid synthesis?

Answer 8

quinolones