Antibiotics Flashcards
cephalosporins
beta-lactam
!st gen cephalosporin
Cefazolin, cefalexin
gm + coverage
2nd gen cephalosporin
cefaclor, cefuroxime
some gm - coverage
3rd gen cephalosporin
Cefotaxime, ceftriaxone
gm - aerobes
Ceftazidime-pseudomonas
4th gen cephalosporin
cefipime
broadest spectrum
Carbapenems
Broadest spectrum beta-lactams
inipenem (broadest spectrum of all ATB’s)
merepenem
Monobactam
beta-lactam
aztreonam
gm - only
Tetracyclines
protein synthesis inhibitors
tetracycline, doxycycline,
broad spectrum
macrolide drug of choice for PCN allergy
erythromycin
gm + and some gm -
drug of choice in PCN allergic pts
other macrolides
azithromycin
clarithromycin (biaxin)
Cleocin
gm - and gm + anaerobes and some gm + areobes
associated with development of Cdiff
Linezolid/zyvox
VRE, MRSA
Aminoglycosides
Gent, tobra, amikasin
aerobic Gm - bacilli
nephro and oto toxic
sulfa-trimethoprim
broad spectrum
UTI’s , p. carinii
Bacteriocidal drugs
Fluroquinolones
metronidazole (anearobic infections)