Antibiotics Flashcards

1
Q

cephalosporins

A

beta-lactam

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2
Q

!st gen cephalosporin

A

Cefazolin, cefalexin

gm + coverage

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3
Q

2nd gen cephalosporin

A

cefaclor, cefuroxime

some gm - coverage

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4
Q

3rd gen cephalosporin

A

Cefotaxime, ceftriaxone

gm - aerobes

Ceftazidime-pseudomonas

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5
Q

4th gen cephalosporin

A

cefipime

broadest spectrum

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6
Q

Carbapenems

A

Broadest spectrum beta-lactams

inipenem (broadest spectrum of all ATB’s)

merepenem

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7
Q

Monobactam

A

beta-lactam

aztreonam

gm - only

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8
Q

Tetracyclines

A

protein synthesis inhibitors

tetracycline, doxycycline,

broad spectrum

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9
Q

macrolide drug of choice for PCN allergy

A

erythromycin

gm + and some gm -

drug of choice in PCN allergic pts

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10
Q

other macrolides

A

azithromycin

clarithromycin (biaxin)

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11
Q

Cleocin

A

gm - and gm + anaerobes and some gm + areobes

associated with development of Cdiff

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12
Q

Linezolid/zyvox

A

VRE, MRSA

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13
Q

Aminoglycosides

A

Gent, tobra, amikasin

aerobic Gm - bacilli

nephro and oto toxic

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14
Q

sulfa-trimethoprim

A

broad spectrum

UTI’s , p. carinii

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15
Q

Bacteriocidal drugs

A

Fluroquinolones

metronidazole (anearobic infections)

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16
Q

Fluoroquinolones

A

cipro,moxifloxacin, levofloxacin

broad spectrum

17
Q

Narrow spectrum penicillinase sensitive

A

PCN G, PCN V

18
Q

Narrow spectrum penicillinase resistant

A

nafcillin, oxacillin,

MRSA

19
Q

Broad spectrum PCN

A

amoxicillin, ampicillin

H.Flu, ecoli, gonorhhea

20
Q

extended spectrum PCN

A

piperacillin, ticaricillin

pseudomonas, enterobacter, proteus

21
Q

Pseudomonas coverage

A

PCN+ beta-lactam

Ampicillin + sulbactam (Unasyn)

Amoxicillin + clavulanic acid (Augmentin)

Ticarciliin + clavulanic acid (Timentin)

Piperacillin + tazobactam (Zosyn)

22
Q

Gm Neg

A

H. Flu

(40% of this is beta-lactam resistant)

23
Q

Beta-Lactams

A

Cephalosporins

PCN’s

Ex: primaxin, azactam

24
Q

gram +

A

Strep (may be drug resistant)

25
Q

top 5 conditions that strep pneumoniae causes:

A

meningitis

CAP

sinusitis

OM

Bronchitis