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Antibiotics Flashcards

1
Q

Chronic bronchitis

A

Amoxicillin or Tetracycline

Clarithromycin

5d

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2
Q

CAP

low, moderate and high severity

A

LOW

Amoxicillin 7d

Atypical: + Clarithromycin 14d

PENAL: Doxycycline or Clarithromycin

Staph suspected (post flu): Flucloxacillin

MOD

Amoxicillin + Clarithromycin or Doxycycline alone 7d

MRSA: + Vancomycin

HIGH

Benzylpenicillin + Clarithromycin

or Benzylpenicillin + Doxycycline 7d

Serious/ G+/ Home: Co-amoxiclav + Clarithromycin

MRSA: + Vancomycin

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3
Q

HAP

A

<5d post-admission

  • Co-amoxiclav
  • or Cefuroxime 7d

>5d post-admission

  • Piperacillin with Tazobactam
  • or Cephalosporin broad (eg Ceftazidime)
  • or Quinilone (eg Ciprofloxacin)

MRSA: +Vancomycin

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4
Q

Lower UTI

A

Trimethoprim

or Nitrofurantoin 7d (3d in women)

2nd line: Co-amoxiclav

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5
Q

Acute pyelonephritis

A

Cefuroxime

Quinolone (

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6
Q

Acute prostatitis

A

Quinolone

or Trimethoprim

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7
Q

Impetigo

A

Topical fusidic acid

Widespread;

  • Flucloxacillin
  • or Erythromycin
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8
Q

Cellulitis

A

Flucloxacilline

PENAL: Clarithromycin or Clindomycin

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9
Q

Erysipelas

A

Phenoxymethylpenicillin

PENAL: Erythromycin

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10
Q

Animal or human bite

A

Co-Amoxiclav

PENAL: Doxycycline + Metronidazole

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11
Q

Mastitis during breast feeding

A

Flucloxacillin

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12
Q

Throat infections

A

Phenoxymethylpenicillin

PENAL: Erythromycin

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13
Q

Sinusitis

A

Amoxicillin

or Doxycycline

or Erythromycin

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14
Q

Otitis media

A

Amoxicillin

PENAL: Erythromycin

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15
Q

Otitis externa

A

Flucloxacillin

PENAL: Erythromycin

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16
Q

Periapical or Periodontal abscess

A

Amoxicillin

17
Q

Gingivitis: acute necrotising ulcerative

A

Metronidazole

18
Q

Genital herpes

A

Oral Aciclovir 5x5

19
Q

Genital warts

Condylomata accuminata

HPV 6+11

A
  1. Topical podophyllum (4wk, multiple) or Cryrotherapy (single)
  2. Imiquimod (16wk)
20
Q

Syphilis

A

Benzathine Benzylpenicillin stat (repeat in 6d if 3rd trimester)

or 14d Doxycyline

or 14d Erythromycin

21
Q

Donavanosis

Granuloma inguinale

Klebsiella granulomatis

A

Azithromycin or Doxycyline

Pregnant: Erythromycin

22
Q

Candidiasis (thrush)

A

PO Fluconazole stat

Topical/ pressary: Clotrimazole

23
Q

Trichomonas Vaginalis

A

Metronidazole 2g stat or 400mg/5d

24
Q

Bacterial Vaginosis

A

Metronidazole 2g stat or 400mg/5d

  1. Topical Metronidazole or Clindamycin
25
Q

Chlamydia

A

Azithromycin 1g stat

or Doxycycline 7d

Pregnant: Erythromycin 14d

26
Q

Gonnorrhoea

A

Azithromycin 1g PO stat + Ceftriazone 500mg IM

27
Q

PID

A

Ceftriazone 500mg IM stat + Doxycycline PO 7d

  1. Ofloxacin + Metronidazole PO 14d (not Gonorrhoea)

Severe: IV ceftriazone + metronidazole + doxycycline

28
Q

Campylobacter enteritis

A

Clarithromycin

Alternative Ciprofloxacin

29
Q

Salmonella (non-typhoid)

A

Ciprofloxacin

30
Q

Shigellosis

A

Ciprofloxacin

31
Q

H Pylori

A

7d

  1. PPI
  2. Amoxicillin 1mg
  3. Clarithromycin 500mg bd po or Metronidazole 400mg
32
Q

C. difficile

A

All 10-14d, stop at 10d if asym. Fails move up.

  • Nurse in side room until 72hr symptom free

Mild-mod

  • Metronidazole 400mg PO 8hrly 10-14d

Severe [WCC>15,Cr>50%,temp>38.5,COLITIS]

  • Vancomycin 125mg PO 6hrly

Lifethreatening [hypotension, ilius/ megacolon, severe on CT]

  • Vancomycin 500mg PO 6hrly
    + Metronidazole 500mg IV infusion 8hrly
33
Q

MRSA

  • What is it
  • Screening protocol
  • Management
A

What

  • Methicillin-Resistant Staphylococcus Aureus (MRSA)
  • Resistant to Penicillins + Cephalosporins

MRSA screen 2-4wks prior admission in ALL;

  • + MSSA (Full Staph) screen: Implant/ high risk surgery
  • Swabs
    • Anterior nares (nasal)
    • Any skin lesion
    • Catheterised: CSU (Catheter Specimen of Urine)
    • Productive cough: Sputum
    • Staph screen/ patient tagged: Perineum swab

Blind management

  • >65yrs+transferred from carehome/hospital
  • MRSA Hx in past 6months

Management min 5days and rescreen d7

  • Single room
  • Nasal: Mupirocin 2% 8hrly
  • Skin: Chlorhexidine 0.1% + Neomycin 0.5%
  • Wash body daily
  • Infection
    • Vancomycin, Teicoplanin, Linezolid

ESBL, MGNB, CARB screen

  • ALL patient (unless hasnt been in hospital/ abroad for 1yr)
  • Rectal swab (stoma/ unable: stool sample)
  • Catheter: CSU
  • Management: Microbiologist

ESBL: Extended Spectrum Beta-Lactamase-producing Bacilli

MGNB: Multi-resistant Gram-Negative Bacilli

CARB: Carbapenemase-producing Gram-negative Bacilli

Finals (23 decks)

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