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PHARMACOLOGY > ANTIBIOTICS > Flashcards

ANTIBIOTICS Flashcards

1
Q

What is the MOA of Cephalosporin

A

disrupts cell wall synthesis

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2
Q

What is INDICATION OF Cephalosporin

A

fight infection

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3
Q

What is ADRs of Cephalosporin

A

allergy, bleeding, thrombophlebitis, hemolytic anemia, risk of C. diff
BARTH

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4
Q

What is CONTRAINDICATION OF Cephalosporin

A

alcohol, antacids, iron, oral contraceptives

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5
Q

PATIENT EDUCATION for cephalosporin

A

additional oral contraceptives, no alc,

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6
Q

GENERATIONs of Cephalsporin

A

1st GEN: gram +, limited gram -
2nd GEN: gram+ more gram -
3rd GEN: more gram -, gram +
4th GEN: more gram -, gram +
5th GEN: more gram -, more gram + (MRSA)

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7
Q

What ANTIBIOTICS disrupt cell wall synthesis

A

Cephalosporin
Penicillin,
Vancomysin

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8
Q

If someone has an allergy for penicillin, should the nurse prescribe Cephalosporin?

A

Nurse needs to double check, because cephalosporin and penicillin, have similar structures

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9
Q

What is PENICILLINS MOA

A

disrupts cell wall synthesis

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10
Q

What is Penicillin INDICATION:

A

fight infection

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11
Q

What is Penicillin ADRs

A

allergy, laryngeal edema, bronchoconstriction, severe hypotension
LABS

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12
Q

Patient education for Penicillin

A

take w/ food
use additional oral contraceptives

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13
Q

What is VANCOMYSIN MOA

A

disrupts cell wall synthesis

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14
Q

What is Vancomycin indication

A

fight infections (MRSA) (C.DIFF)

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15
Q

What is Vancomycin ADRs

A

Ototoxicity, nephrotoxicity, Red Man Syndrome, thrombophlebitis, thrombocytopenia, allergy
TARNOT

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16
Q

What is Vancomycin Contraindication

A

Ototoxicity, etc

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17
Q

Patient education for Vancomycin

A

Notify ringing of the ear, DO not take if previous renal problems, don’t drink, age

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18
Q

What antibiotics ALTER PROTEIN SYNTHESIS

A

Aminoglycosides, tetracycline, macrolides

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19
Q

What is Gentamicin MOA

A

bactericidal inhibitor of protein synthesis

20
Q

What is Gentamicin indication

A

kills bacteria

21
Q

What is Gentamicin ADRs

A

ototoxicity, nephrotoxicity

22
Q

Patient education for Gentamicin:

A

preexisting hearing problems or renal damage
no alcohol

23
Q

What is Tetracycline MOA

A

bacteriostatic inhibitor of protein synthesis (Stops growth)

24
Q

What is tetracycline indication

A

stops growth of bacteria

25
Q

What is Tetracycline Contraindications

A

Pregnancy, <8years of age

26
Q

What is Tetracycline ADRs

A

GI Irritation, Bone and teeth (binds to calcium staining teeth), Superinfection, PHOTOSENSITIVITY
PBSG

27
Q

Patient education for Tetracycline

A

DO NOT TAKE with calcium, iron supplements, milk, antacids, magnesium-containing laxatives,
No sun
1hr before, 2 hrs after eating

28
Q

What is antibiotics are Macrolides

A

Erythromycin

29
Q

What is Erythromycin MOA

A

bacteriostatic inhibitor of protein synethsis

30
Q

What is Erythromycin indication

A

Stop bacteria growth

31
Q

What is Erythromycin contraindications

A

Hypersensitive to erythromycin

32
Q

What is Erythromycin ADRs

A

GI Upset, Super infection, cardiac death if given with CYP3A4 inhibitors
CSG

33
Q

Patient Education for Erythromycin:

A

Do not take with food

34
Q

What is Sulfamethoxazole/trimethoprim MOA

A

inhibits sequential steps in bacterial folic acid synthesis ( more powerful than SMX and TMP alone)

35
Q

What is Sulfamethoxazole/trimethoprim Indication

A

UTI, otitis Media, bronchitis, GI infection (BOGU)

36
Q

What is sulfamethoxazole/trimethoprim. ADR

A

GI (vomiting and nausea), rash, hyperkalemia, Steven-johnsons (RHGS)

37
Q

Patient education for Sulfamethoxazole/trimethoprim

A

NO sun

38
Q

What is Sulfonamides MOA

A

Suppresses bacterial growth by inhibiting tetrahydrolic acid
- inhibits bacterial synthesis of folic acid

39
Q

What is Sulfonamides Indication

A

Acute and uncomplicated UTI, Chlymadia ttrachomatis,
AC

40
Q

What is Sulfonamides ADR

A

Allergy, hyperkalemia, birth defects, Steven Johnson, hemolytic anemia, kerniticus, renal damage
KRABSHH

41
Q

Patient education for Sulfonamides

A

No alc
Preexisting renal damage

42
Q

What is Ciprofloxacin MOA:

A

(bactericidal) Inhibits bacterial DNA enzymes

43
Q

What is Ciprofloxacins Indication

A

kills bacteria

44
Q

What is CIprofloxacins ADRs

A

Tendinitis, tendon rupture, QT pronlongationW
QTT

45
Q

What is Ciprofloxain BLACK BOX

A

tendinitis, tendon rupture

PHARMACOLOGY (4 decks)

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