Antibiotics: Flashcards
Bacteriostatic
folate syn inhibit
sulf-
Sulfonamides
-cidal
DNA syn inhibitors
-floxacins
Fluoroquinones
Which ABX are B-lactams and what do they do?
Penicillins, Cephalosporins, Monobactams, Carbapenems
inhibit cell wall synthesis
-cidal
wide range
allergy to this also has allergy to cephalospoirins
penicillins
pen g is which verse and why
IV because it is degraded in acid and if oral then it would degredae in stomach
Pen v is what
oral
Augmentin
amx and clauvanic acid (b-lactamse resistance)
Ampicillin is what
most effecttive penicllin with gram- infection
Cef-
cell wall inhibitors
cephalosporins
- ams
cell wall syn inhibitors
monobactams
-nems
cell wall synthesis inhibitors
carbapenems
-static
inhibits the 30s ribsosomal subunit inhibiting protein synthesis
BROADEST SPECTRUM
Tetracylcines
Where do tetracylcines most commonly aggregate?
in the GCF
Where does clindamycin most commonly aggregate?
in the bones
- static
50s subunit
protein synthesis inhibitor
BOTH Macrolides and Lincosamides
Mac Likes to Thro Myc - erthromycin
linc also hides myc - lincosamide
Which cardi need proph abx
prothetic heart valves
history of IE
Heart transplant with regurt/ valvopathy
congential heart defect
Which compromised immunity need prophy abx
organ trans
neutropenia
cancer therapy
What is the dose for first choice abx for IC
2 g of amox
abx for kids with IE?
50 mg of Amox
abx for pt with PCN allergy
Clindamycin 600 mg
kid with PCN allergy
250 mg of CLinda
Non-oral (IV or IM)
ampicillin 2 g (3o min before tx)
CHildren non oral
ampicillin 50 mg 30 m before tx
What is the first choice of ABX for artficial joint repalcement
Keflex 2 g 1 hr before t
What is the side effect with clinda
psuedomemb colitis
what causes superinfection
broad spectrum abx
Which is associated with aplastic anemia
chloramphenicol
What causes liver damage
tetracylcine
what is associated with allergic cholestatic hepatitis
erythromycin estolate
What drugs help treat viral ifx like herpes?
-virs
acyclovir and valcyvclovir
what are used to tx fungals? Like candiaisiss
fluconazole
-azoles
what antifungal is found in troche form?
mycelex (clotrimazole
What is the max dose of Lidocaine (2% without epinephrine)
4.4 mg
What is the max dose of Lidocaine (2% with 1:100,000 epinephrine)
Adult 7 and child is 4.4
What is the max dose of Articaine (4% with 1:100,000 epinephrine)
7
What is the max dose of Mepivacaine (3% without epinephrine)
4.4
What is the max dose of
