Antibiotics Flashcards

1
Q

What infections are caused by gram-positive bacteria?

A
  • UTI
  • MRSA
  • Pneumonia
  • Gonorrhea
  • C.diff
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2
Q

Which infections are caused by gram-negative bacteria?

A
  • Gastroenteritis
  • Pneumonia
  • Meningitis
  • Sepsis
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3
Q

Examples of gram-positive bacteria?

A

Staphylococcus, Streptococcus, Enterococcus

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4
Q

Examples of gram-negative bacteria?

A

Acinetobacter, Pseudomonas aeruginosa and E.coli

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5
Q

What antibiotic can cause dark urine?

A

Nitrofurantoin

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6
Q

What antibiotic causes teeth discolouration in children?

A

Tetracyclines

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7
Q

What is the first line treatment for C.diff infection

A

1) Nitrofurantoin

2) Trimethoprim

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8
Q

What antibiotics should be avoided in pregnancy?

A
  • Tetracyclines
  • Nitrofurantoin (close to term)
  • Trimethoprim (first trimester)
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9
Q

What drug class is used as an alternative in penicillin allergy?

A

Macrolides

  • Clarithromycin
  • Erythromycin
  • Azithromycin
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10
Q

Wha is the first line treatment for pneumonia?

A

Amoxicillin

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11
Q

Which organism cultured from sputum indicates treatment MUST be started?

A

Group A Beta Haemolytic Streptococcus

  • Linked to 2 potentially serious complications: rheumatic fever and acute glomerulonephritis
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12
Q

What antibiotics are used in treatment of tuberculosis?

A

Rifampin
Isoniazid
Pyrazinamide
Ethambutol

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13
Q

What are the common side effects of the treatment for tuberculosis?

A

Rifampin - red/orange urine and bodily fluids
Isoniazid - peripheral neuritis
Pyrazinamide - hyperuricaemia
Ethambutol - decreased visual acuity

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14
Q

What is the list line treatment for strep throat?

A

Phenoxymethylpenicillin

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15
Q

What is the first line treatment for acne vulgaris

A

Doxycycline

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16
Q

What is the first line treatment for gonorrhoea?

A

Ceftriaxone

17
Q

What is the first line treatment for chlamydia?

A

Azithromycin

18
Q

What is the MOA of trimethoprim?

A

Inhibits bacterial folate synthesis

19
Q

What is the MOA of fluoroquinolone antibiotics (ciprofloxacin) ?

A

Inhibits DNA synthesis

20
Q

What is the MOA of macrolides bacteria?

A

Inhibits bacterial protein synthesis

21
Q

What is the MOA of amoxicillin?

A

Weaken bacterial cell walls