Antibiotics Flashcards

1
Q

Sepsis

A

co-amox + gentamicin + metronidazole if suspect anaerobic

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2
Q

CAP with sepsis

A

co-amox + clarithromycin + gentamicin if severe

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3
Q

CAP without sepsis, CURB-65: 0-1

A

amoxicillin

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4
Q

CAP without sepsis, CURB-65: 2-5

A

amoxicillin + doxycycline

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5
Q

Intra-abdominal sepsis (luminal/biliary)

A

source control + co-amox + metronidazole if delayed source control/complex abscess

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6
Q

CNS infection, assumed bacterial

A

ceftriaxone + dexamethasone

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7
Q

CNS infection, viral features

A

+ acyclovir (features = obtundation, seizures, confusion)

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8
Q

Warfarin levels increase after these Abx

A

clarithromycin/ciprofloxacin

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9
Q

Warfarin levels decrease after this Abx

A

Rifampicin

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10
Q

Abx contraindicated in first trimester

A

Trimethoprim (neural tube defects)

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11
Q

Abx contraindicated at term

A

nitrofurantoin (neonatal haemolysis)

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12
Q

Pseudomonas Abx

A

Ciprofloxacin (only oral), gentamicin, pip-taz, meropenem, ceftazidime
= when immunosuppressed (neutropenic sepsis)

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13
Q

Gentamicin toxicity

A

nephrotoxic and ototoxic

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14
Q

MRSA

A

vancomycin

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15
Q

Extended spectrum β-lactamase infection

A

carbapenem e.g. meropenem

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16
Q

Criteria to diagnose UTI

A

Positive urinalysis AND symptoms (dysuria, frequency, urgency)

17
Q

UTI + sepsis

A

co-amoxiclav + single dose gentamicin

18
Q

Catheter associated UTI without symptoms

A

No treatment

19
Q

Catheter associated UTI with symptoms

A

co-amoxiclav and catheter change (source control)

20
Q

UTI with upper urinary tract symptoms (pyelonephritis)

A

co-amoxiclav

21
Q

UTI with prostatitis

A

Ciprofloxacin (oral) or co-amoxiclav + single dose gentamicin

22
Q

UTI without prostatitis

A

nitrofurantoin

23
Q

UTI in female

A

nitrofurantoin

24
Q

Pseudomembranous colitis (diarrhoea after Abx) causative organism

A

c. diff

25
Q

Necrotising fasciitis

A

s. aureus

co-amox + clindamycin (+ vancomycin if MRSA)

26
Q

Mild diabetic foot ulcer (or non-diabetic)

A

flucloxacillin (+ co-trimoxazole if MRSA+)

27
Q

Moderate diabetic foot ulcer

A

co-amoxiclav

28
Q

Severe diabetic foot ulcer

A

co-amoxiclav + gentamicin + pip-taz

29
Q

c difficile Abx

A

metronidazole

30
Q

bronchitis Abx

A

doxy

31
Q

mild allergy to penicillin - replacement

A

cephalosporins e.g. cefuroxime

32
Q

lifestyle advice when taking metronidazole

A

alcohol avoidance - associated with disulfiram like reaction

33
Q

infective exacerbation of COPD

A

amoxicillin or doxycycline