Antibiotics Flashcards
Sepsis
co-amox + gentamicin + metronidazole if suspect anaerobic
CAP with sepsis
co-amox + clarithromycin + gentamicin if severe
CAP without sepsis, CURB-65: 0-1
amoxicillin
CAP without sepsis, CURB-65: 2-5
amoxicillin + doxycycline
Intra-abdominal sepsis (luminal/biliary)
source control + co-amox + metronidazole if delayed source control/complex abscess
CNS infection, assumed bacterial
ceftriaxone + dexamethasone
CNS infection, viral features
+ acyclovir (features = obtundation, seizures, confusion)
Warfarin levels increase after these Abx
clarithromycin/ciprofloxacin
Warfarin levels decrease after this Abx
Rifampicin
Abx contraindicated in first trimester
Trimethoprim (neural tube defects)
Abx contraindicated at term
nitrofurantoin (neonatal haemolysis)
Pseudomonas Abx
Ciprofloxacin (only oral), gentamicin, pip-taz, meropenem, ceftazidime
= when immunosuppressed (neutropenic sepsis)
Gentamicin toxicity
nephrotoxic and ototoxic
MRSA
vancomycin
Extended spectrum β-lactamase infection
carbapenem e.g. meropenem