Antibiotici Flashcards

1
Q

Podela antibiotika koji sprečavaju rast ćelisjkog zida.

A

Beta laktamski
batracin
glikopeptid
etambutol
izoniazid

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2
Q

Beta - laktamski antibiotici.

A

penicilin
karbapenemi
ciklosporin
monobaktam

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3
Q

Podela penicilina prema supstratu na koji deluju.

A

antistafilokokni
aminopenicilini
ureidopenicilini

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4
Q

Na koga deluju penicilini?

A

gram+
neke spirohete i neke g -

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5
Q

Najbrojniji antibiotici?

A

Cefalosporini

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6
Q

Ko su PVP?

A

transpeptidaza i transglikozidaza

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7
Q

Antibiotici koji deluju na ćelijsku membranu

A

Polimiksin i daptomicin

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8
Q

Antibiotici koji se vezuju za 30S.

A

tetraciklini
aminoglikozidi

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9
Q

Na koje strukture bakterijske ćelije deluju antibiotici?

A

Ćelijski zid
ćelijska membrana
ribozomi
nukleinske kiseline i put folne kiseline

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10
Q

Antibiotici moji se vezuju za 50 S.

A

Aminoglikozidi
linkozamidi
hloramfenikol

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11
Q

Aminoglikozidi

A

-baktericidno dejstvo
-30S
-sinergizam sa beta laktamskim antibiotiima
-strptomicin
- gram-
-ne apsorbuju se iz digestivnog trakta pa se daju intravenski, intramuskularno ili lokalno

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12
Q

Na koje bakterije deluju glikopeptidi?

A

Samo na gram pozitivne.

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13
Q

Na šta deluju izoniazid i etambutol?

A

Na Mycobacterium.

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14
Q

Antibiotici koji deluju na RNK?

A

Rifampicin

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15
Q

Antibiotici koji deluju na DNK?

A

Fluorohinoloni
Metroidazol

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16
Q

Antibiotici širokog spektra

A

Cefalosporini, tetraciklini

17
Q

Antibiotici uskog spektra

A

vankomicin i penicilin

18
Q

Aminopenicilin

A

Amoksicilin
na gram-

19
Q

Za šta se kači vankovicin.

A

NAM

20
Q

Za šta se kači penicilin?

A

transpeptidaze

21
Q

Tetraciklini

A

-bakteristatsko dejstvo
-tetraciklin, doksiciklin, glicilciklin
-ne daju se trudnicama i maloj deci
-bakterijama koje nemaju ć zid, intracelularnim bakterijam, lajmska bolest

22
Q

Daj primer sinergizma antibiotika?

A

Aminoglikozidi i betalaktamski antibiotici

23
Q

Azitromicin se daje protiv…

A

gram +, Helicobacterpylori

24
Q

Hloramfenikol

A

-širok spektar delovanja
-prolazi kroz hemocefaličnu barijeru
-anemije

25
Q

Kada kombinujemo 2 antibiotika?

A
  1. proširivanje spektra delovanja
  2. sprečavanje rezistencije na antibiotike
    3.sinergistički efekat
26
Q

Antituberkulotici 1. klse

A

Izoniazid
Etambutol
Rifampicin
Streptomicin

27
Q

Na koji enzim deluju fluorohinoloni?

A

DNK girazu

28
Q

Antituberkulotici 2. reda

A

aminoglikozidi
cikloserin
poliptidi
fluorohinuloni

29
Q

Antibiotici kaji deluju nam metabolički put folne kiseline.

A

sulfoamidi i trimetoprim