Mehanizmi odbrane bakterija Flashcards

1
Q

Vrste rezistencije bakterija

A

stečena i urodjena

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2
Q

Gde se nalaze geni razistencije?

A

Hromozomska i Ekstrahromozomska DNK (plazmidi, transpozomi, bakteriofagi)

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3
Q

Razlozi zašto bakterije mogu da budu osetljive na antibiotike?

A

1.slaba propustljivost kroz ćelijski zid
2.nemaju ciljna mesta na koje deluju natibiotici
3.imaju enzime koji razgradjuju antibiotike

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4
Q

Gram - bakterije su osetljive na….

A

vankomicin, bacitracin, linezoid

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5
Q

Najlakši način stvaranje rezistencije

A

preko plazmida u konjugaciji

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6
Q

Koje klase bakterija su razvile multirezistentnost?

A

enterobakterije
gram - nefermentni bacili
stafilokoke, enterokokoe C. difficile

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7
Q

Gde se nalaze geni za enzime

A

Na plazmidima

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8
Q

Ko stvara beta laktamaze

A

GRAM —
gram +

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9
Q

Koje gram + bakterije produkuju beta laktamaze

A

Stafilokoke i enterokoke

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10
Q

Medicinski najznačajnije beta laktamaze

A

Karbapenemaze
Beta laktamaze proširnog spektra delovanja

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11
Q

Štav rade ESBL

A

razgradnja cefalosporina prve 3 generacije

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12
Q

Najznačajniji produktori ESBL i karabapenemaza

A

Enterobakterije i nefermentativni bacili

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13
Q

Kako se transportuju geni koji kodiraju enzime koji se ključni za promenu mesta vezivanja antibiotika?

A

transormazijom
transpozoni
bakteriofagi

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14
Q

Izmena ribozoma je značajna za koju vrstu bakterija

A

Gram +

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15
Q

Izmena DNK topoizomeraza je zastupljena kod

A

pneumokok
Kohov bacil
enterokok

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16
Q

Smanjen influks je karakterističan za…

A

Gram -

17
Q

Bakterije sa velikom rezistencijom

A

-MRSA i stafilokok rezistentan na vankomicin
-VRE
-multirezistentni sojevi Mycobacterium tuberculosis
-