Antibiotic coverage &SE Flashcards

0
Q

Cephalosporins

A

Hypersensitivity

Risk for C.diff

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1
Q

Penicillins

A

Hypersensitivity
Nephrotoxicity
Hematologic

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2
Q

False positive Coobs test

A

Cefepime

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3
Q

Biliary sludging

A

Ceftriaxone- under 1month

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4
Q

Serum sickness

A

Cefaclor

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5
Q

Bacteroids

Cephalosporins

A

Cefoxitin (Mefoxin)
Cefotetan (Cefotan)
Ceftolazane/tazobactam (Zerbaxa)

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6
Q

Pseudomonas

Cephalosporin

A

Ceftolazane/tazobactam( Zerbaxa )
Ceftazidime (Fortaz)
Cefepime (Maxipime)

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7
Q

HEN PEK

A

H. Influenza
Enterobacter
Neisseria

Proteus
E.coli
Klebsiella

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8
Q

Cephalosporin resistant bacterial

A

Atypical
Enterococcus
Listeria

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9
Q

Carbapenems

A
Seizure risk (imipenem)
Hypersensitivity
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10
Q

Glycopeptide

A

Nephrotoxicity
Ototoxicity
Red-man syndrome
RBW dose

QT: telavancin
Bleeding: Orbactiv

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11
Q

Lipopeptide

A

Myopathy

Monitor CK: d/c > 10x

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12
Q

AG

A
Nephrotoxicity
Ototoxicity
PAE
IBW dose 
Synergy dose for gram +
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13
Q

TC/GC

A
Photosensitivity
Take with water and stand for 30min
N/V 
Pregnancy category D 
Reduce OC effect 
Chelation
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14
Q

Macrolide/ ketolide

A

GI, QT, CYP 450 DDI,

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15
Q

Dificid

A

Only for c.diff

Block RNA synthesis by inhibiting RNA transcription

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16
Q

Lincosamide

A

Increase CDI. C. Diff

Require D-test

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17
Q

Oxazolidinones

A

Thrombocytopenia

Serotonin syndrome

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18
Q

FQs

A
C.diff risk
CNS in elderly
QT prolongation
Tendinitis and rupture 
Photosensitivity
Chelation
Contraindication in pregnancy 
DDI with warfarin.
19
Q

Flagyl

A
Disulfiram reaction
Metallic taste 
Stomatitis
Peripheral neuropathy
Avoid in 1st tri and feeding
20
Q

Bactrim

A

Sulfa allergy
GI, Hematologic
Avoid in pregnancy

Good for CSF Meningitis

21
Q

Nitrofurantoin

A

Ineffective when renal under 40-50

Bactericidal only for UTI ( high concentration in bladder)

22
Q

Rifampin

A

Fluid discoloration
Hepatotoxicity
CYP450 DDI
RIFABUTIN BETTER THAN RIFAMPIN

23
Q

Colistin

A

Polymyxin
Available IV/IM/ inhalation

Nephrotoxicity elevated Scr/BUN
neurotoxicity

24
Drug cause QT
Fuck TV kills me FQ, Telavancin, ketolide, macrolide
25
Drug increase bleeding
F bad menstrual FQ, Bactrim, Metronidazole
26
Cannot give to preg
F bad trimester FQ, bectrim, tetracycline
27
C. Diff
increase: clindamycin, FQs, Cephalosporins Treatment: Metronidazole, Dificid, vanco PO 125 bid
28
Atypical
Let my chance, F my term Legionella, mycoplasma, chlamydia FQ, macrolide, tetracycline
29
Pseudomonas
F AN ZEBRA hit MONOPOLY CAR at MAXIUM FORCE when pass TIME ZONE at FOLSOM FQ, AG, Zerbaxa, Aztreonam, polymyxins, carbapenem, Maxipime, Fortaz, Timentin, Zosyn, Fosfumycin
30
No renal needed
PRP (DON) Protein inhibitors except AG ROCEPHIN RECEIVE MEXICO FLAG ON FOLSOM Rocephin, Rifampin, Moxifloxacin, Flagyl, Orbactiv, Fosfumycin
31
Bad liver
MIKE RECYCLE a CLEAN RED METRIX Macro/Ketolide, Cycline, Clindamycin, Rafampin, Metronidazole
32
Bacteristatic
Protein inhibitors w/o AG + low dose Rifampin
33
Bactericidal
AG wall synthesis DNA
34
Enterococcus
Amy & Syner aGree to aDapt Little Tiger DOC: Aminopenicillin Glycopeptide, daptomycin, linezolid, Synercid, tigecycline
35
VRE
Syner aDopt Little Tiger on TV Daptomycin, Tigacycline, Linezolid, Telavancin Synercid: E. faecium only
36
Above Anaerobic (pepto, provotella, fusobactrium)
Penicillin V, BLIC, Clindamycin, Carbapenems
37
Below anaerobic ( Bacteroids, fusobactrium)
BLIC, Carbapenem, metronidazole, tigacycline, Clindamycin, cefotetan, cefoxitin, Zerbaxa
38
MSSA
PRP, BLIC, Cephalosporin except Maxipime , Carbapenems, Glycopeptide, Daptomycin, TC, FQ, Clindamycin, Synercid, Linzolid, Bactrim, Fosfumycin, Rifampin
39
MRSA -HA
STT DOG Synercid, Teflaro, Tigecycle, Daptomycin, Oxazolidinones, Glycopeptide
40
MRSA
BOLT Bactrim, Oxazolidinones, Lincosamide, TC
41
BE PSEUDO
Burn, endocarditis | Peumonia, Sepsis, external otitis media, UTI, Diabetic Osteomyelitis
42
ES KAPE
E. Faceium, S. Aureus, | K. Pneumonia, A. Baumannii, P. Aeruginosa, Enterobacter Spp
43
PRSP
Ceftazidime, Cefepime, Vancomycin, Daptomycin, Linezolid, telavancin, Synercid
44
Time dependent
BL Totally Cool; Mac's Van w/ Tiger Sen. BL, TC, Clindamycin, Macrolide, Tigacycline, Synercid
45
Concentration dependent
FAM DOT N TOP FQ, AG, metronidazole, Daptomycin, Orbactiv, Telavancin, Nitrofurantoin, telithromycin, Oxazolidinones, polymyxins
46
Gram+
GL, DL, R Glycopeptide, Daptomycin, Linezolid, Lincosamide, Rifamycin