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pharmacy > Antibiotic coverage &SE > Flashcards

Antibiotic coverage &SE Flashcards

0
Q

Cephalosporins

A

Hypersensitivity

Risk for C.diff

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1
Q

Penicillins

A

Hypersensitivity
Nephrotoxicity
Hematologic

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2
Q

False positive Coobs test

A

Cefepime

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3
Q

Biliary sludging

A

Ceftriaxone- under 1month

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4
Q

Serum sickness

A

Cefaclor

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5
Q

Bacteroids

Cephalosporins

A

Cefoxitin (Mefoxin)
Cefotetan (Cefotan)
Ceftolazane/tazobactam (Zerbaxa)

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6
Q

Pseudomonas

Cephalosporin

A

Ceftolazane/tazobactam( Zerbaxa )
Ceftazidime (Fortaz)
Cefepime (Maxipime)

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7
Q

HEN PEK

A

H. Influenza
Enterobacter
Neisseria

Proteus
E.coli
Klebsiella

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8
Q

Cephalosporin resistant bacterial

A

Atypical
Enterococcus
Listeria

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9
Q

Carbapenems

A 
Seizure risk (imipenem)
Hypersensitivity
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10
Q

Glycopeptide

A

Nephrotoxicity
Ototoxicity
Red-man syndrome
RBW dose

QT: telavancin
Bleeding: Orbactiv

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11
Q

Lipopeptide

A

Myopathy

Monitor CK: d/c > 10x

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12
Q

AG

A 
Nephrotoxicity
Ototoxicity
PAE
IBW dose 
Synergy dose for gram +
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13
Q

TC/GC

A 
Photosensitivity
Take with water and stand for 30min
N/V 
Pregnancy category D 
Reduce OC effect 
Chelation
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14
Q

Macrolide/ ketolide

A

GI, QT, CYP 450 DDI,

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15
Q

Dificid

A

Only for c.diff

Block RNA synthesis by inhibiting RNA transcription

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16
Q

Lincosamide

A

Increase CDI. C. Diff

Require D-test

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17
Q

Oxazolidinones

A

Thrombocytopenia

Serotonin syndrome

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18
Q

FQs

A 
C.diff risk
CNS in elderly
QT prolongation
Tendinitis and rupture 
Photosensitivity
Chelation
Contraindication in pregnancy 
DDI with warfarin.
19
Q

Flagyl

A 
Disulfiram reaction
Metallic taste 
Stomatitis
Peripheral neuropathy
Avoid in 1st tri and feeding
20
Q

Bactrim

A

Sulfa allergy
GI, Hematologic
Avoid in pregnancy

Good for CSF Meningitis

21
Q

Nitrofurantoin

A

Ineffective when renal under 40-50

Bactericidal only for UTI ( high concentration in bladder)

22
Q

Rifampin

A

Fluid discoloration
Hepatotoxicity
CYP450 DDI
RIFABUTIN BETTER THAN RIFAMPIN

23
Q

Colistin

A

Polymyxin
Available IV/IM/ inhalation

Nephrotoxicity elevated Scr/BUN
neurotoxicity

24
Q

Drug cause QT

A

Fuck TV kills me

FQ, Telavancin, ketolide, macrolide

25
Q

Drug increase bleeding

A

F bad menstrual

FQ, Bactrim, Metronidazole

26
Q

Cannot give to preg

A

F bad trimester

FQ, bectrim, tetracycline

27
Q

C. Diff

A

increase: clindamycin, FQs, Cephalosporins

Treatment:
Metronidazole, Dificid, vanco PO 125 bid

28
Q

Atypical

A

Let my chance, F my term

Legionella, mycoplasma, chlamydia
FQ, macrolide, tetracycline

29
Q

Pseudomonas

A

F AN ZEBRA hit MONOPOLY CAR at MAXIUM FORCE when pass TIME ZONE at FOLSOM

FQ, AG, Zerbaxa, Aztreonam, polymyxins, carbapenem, Maxipime, Fortaz, Timentin, Zosyn, Fosfumycin

30
Q

No renal needed

A

PRP (DON)
Protein inhibitors except AG

ROCEPHIN RECEIVE MEXICO FLAG ON FOLSOM
Rocephin, Rifampin, Moxifloxacin, Flagyl, Orbactiv, Fosfumycin

31
Q

Bad liver

A

MIKE RECYCLE a CLEAN RED METRIX

Macro/Ketolide, Cycline, Clindamycin, Rafampin, Metronidazole

32
Q

Bacteristatic

A

Protein inhibitors w/o AG + low dose Rifampin

33
Q

Bactericidal

A

AG wall synthesis DNA

34
Q

Enterococcus

A

Amy & Syner aGree to aDapt Little Tiger

DOC: Aminopenicillin

Glycopeptide, daptomycin, linezolid, Synercid, tigecycline

35
Q

VRE

A

Syner aDopt Little Tiger on TV
Daptomycin, Tigacycline, Linezolid, Telavancin

Synercid: E. faecium only

36
Q

Above Anaerobic (pepto, provotella, fusobactrium)

A

Penicillin V, BLIC, Clindamycin, Carbapenems

37
Q

Below anaerobic ( Bacteroids, fusobactrium)

A

BLIC, Carbapenem, metronidazole, tigacycline, Clindamycin, cefotetan, cefoxitin, Zerbaxa

38
Q

MSSA

A

PRP, BLIC, Cephalosporin except Maxipime , Carbapenems, Glycopeptide, Daptomycin, TC, FQ, Clindamycin, Synercid, Linzolid, Bactrim, Fosfumycin, Rifampin

39
Q

MRSA -HA

A

STT DOG

Synercid, Teflaro, Tigecycle, Daptomycin, Oxazolidinones, Glycopeptide

40
Q

MRSA

A

BOLT

Bactrim, Oxazolidinones, Lincosamide, TC

41
Q

BE PSEUDO

A

Burn, endocarditis

Peumonia, Sepsis, external otitis media, UTI, Diabetic Osteomyelitis

42
Q

ES KAPE

A

E. Faceium, S. Aureus,

K. Pneumonia, A. Baumannii, P. Aeruginosa, Enterobacter Spp

43
Q

PRSP

A

Ceftazidime, Cefepime, Vancomycin, Daptomycin, Linezolid, telavancin, Synercid

44
Q

Time dependent

A

BL Totally Cool; Mac’s Van w/ Tiger Sen.

BL, TC, Clindamycin, Macrolide, Tigacycline, Synercid

45
Q

Concentration dependent

A

FAM DOT N TOP

FQ, AG, metronidazole, Daptomycin, Orbactiv, Telavancin, Nitrofurantoin, telithromycin, Oxazolidinones, polymyxins

46
Q

Gram+

A

GL, DL, R

Glycopeptide, Daptomycin, Linezolid, Lincosamide, Rifamycin

pharmacy (15 decks)

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