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Pharm Unit 4 by Hans Kim > antiarrythmic 2 > Flashcards

antiarrythmic 2 Flashcards

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1
Q

what drug has stronger K+ channels blocker than beta adrenergic receptor antagonist?

A

sotalol

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2
Q

what has the multiple actions on Na, K, Ca channel blockers or alpha, beta receptor antagonist?

A

amiodarone

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3
Q

what is the mech of class IA?

A

fast Na+ channel blocker

  • -> prolongs effective refractory period
  • -> prolongs action potential duration
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4
Q

what is the alternative drug for chronic treatment of atrial flutter, fibrillation, SVT?

A

Quinidine

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5
Q

what other effects do quinidine have?

A
  1. alpha adrenergic blockade
  2. M2 blockade
  3. vagal inhibtion
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6
Q

what are the toxicities of class IA?

A
  1. diarrhea
  2. nausea
  3. fever
  4. hepatitis
  5. thrombocytopenia
  6. cinchonism
  7. QT prolongation
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Pharm Unit 4 by Hans Kim (15 decks)

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