Antiarrthmitic

Question 1

Lignocaine

Answer 1

action 15 m 
inactive orally 
Na blockers
effective for V tacky arrhythmia 
inhibith purkinji

Question 2

Class 1 Agents

Answer 2

1A : 
Double quarter pounder 
Quaindine,procainamide, Disopyramide 
 1B :
Lignocaine,phenytoin 
1C: 
flecainide

Question 3

Esmolol

Answer 3

short acting

use foe arrhythmia after anasthesia

Question 4

class 2 B blocker

Answer 4

MOA : reduce Adrenaline + NA
Decrease sinus node automaticity

uses:
AF
post MI

Question 5

Class 3 (SAB)

Answer 5

ex: sotalol,Amiodatone,Bretylium

Prolong AP by Block eflux K
prolong refractory period (increased QT interval)

Question 6

Amiodarone

Answer 6

class 3 
used for supraventricular and ventricular tachycardia

Question 7

Bretlium

Answer 7

Class 3

Adrenergic neuron blocker

Question 8

Class 3 AE

Answer 8

thyroid dysfunction 
pneumonia 
liver toxicity 
skin discoloration 
Irregular a QRS complex is which appear to be twisting around the ECG  baseline

Question 9

Class 4

Answer 9

MOA : Block slow Ca entry responsible for conduction Knodell tissue
Suppress normal and abnormal automaticity

ex: verapamil,dilitazam

Question 10

veramil

Answer 10

used :

orally for A trail fibrillation + to prevent recurrence of paroxysmal supraventricle tachycardia

Question 11

adenosine

Answer 11

IV , short 20 s
proper conversion of Supraventricular tachycardia to sinus rhythm

MOA
reduce Ca in AV node

AE chest tightness Dispnea hypotension, flushing

Question 12

Digoxine

Answer 12

Block AV conduction
‏ slow ventricle rate in atrial fibrillation

use:
treatment of low output heart failure in patients who are symptomatic despite optimal use of diuretic ACE inhibitors and beta-blockers

MOA:
to slow V rate in AF :
‏ stimulate vagus nerve with consequent reduced AV conduction
therapy slow ventricle rate