Antiarritmicos Flashcards

1
Q

Qué clase de antiarritmicos son el verapamilo y diltiazem?

A

NO DHP - Clase IV

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2
Q

Qué clase es la adenosina?

A

Clase IV de antiarritmicos similares

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3
Q

Efectos adversos antiarritmicos

A

Arritmias torsade pointes

Taquicardia ventricular de puntas torcidas

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4
Q

Indicaciones antiarritmicos

A

Solo si el corazón es estructuralmente normal

Solo en taquicardias

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5
Q

Efectos adversos AMIODARONA (clase III) - QT

A

Arritmias mortales
Postdespolarizacion temprana: torsade de pointes

Postdespolarizacion tardía: taquicardia ventricular (etapa 3-4)

Fibrosis pulmonar

Disfunción tiroidea

Toxicidad hepatica (elevación transaminasas)

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6
Q

Revertir toxicidad por amiodarona

A

Dronedarona

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7
Q

Dosis mantenimiento de amiodarona

A

200 mg en 1 día

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8
Q

Fase donde interviene fármacos clase 1 de antiarritmicos

A

Bloqueo canales de Na: fase 0

  • reduce frec maxima de despolarizacion
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9
Q

Grupos de clase 1 de antiarritmicos

A

A: procainamida - QT (torsade de pointes)

B: lidocaina - fase 0 = acorta periodo refractario

C: Flecainida y propafenona = alarga periodo refractario: aumentan QRS

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10
Q

Grupo más utilizado de la clase 1 de antiarritmicos

A

Subdivisión 1C

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11
Q

Clase II de antiarritmicos

A

BB

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12
Q

Fase de acción de los BB

A

Fase 4 es menos activa - + lento el potencial de acción

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13
Q

Clase III antiarritmicos

A

Bloq canal k

- fase III

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14
Q

Fármacos bloq cáñales de K

A

AMIODARONA

Sotalol

Dofetilde

Ibutilde

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15
Q

Efectos adversos bloq cala K

A

Postdespolarizacion temprana (TP) y tardía (taquicardia ventricular fase 3 y 4)

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16
Q

Fármacos de clase IV antiarritmicos

A

Verapamilo
Diapazem

ADENOSINA: abren canal de K —- indirectamente Ca