Antiarrhythmics/Heart Failure

Question 1

Class IA Overview

Answer 1

Increases AP Duration (lengthens)

Question 2

Class 1B Overview

Answer 2

Shorten duration of AP and refractory period

Question 3

Class 1C Overview

Answer 3

No or little effect on the duration of AP or refractory period

Question 4

Class II

Answer 4

B-adrenoceptor blocker

Question 5

Class III

Answer 5

K+ channel blockers

Question 6

Class IV

Answer 6

Ca 2+ channel blockers

Question 7

Class 1A Medications

Answer 7

Quinidine
Procainamide
Disopyramide

Question 8

Class 1A Medication ADR

Answer 8

Prolonged QT Interval
Induction of torsades de pointes
Nausea

Question 9

Class 1B Medications

Answer 9

Lidocaine

Mexiletine

Question 10

Class 1B Medications ADR

Answer 10

Hypotension
Tremor
Lightheadedness

Question 11

Class 1C Medications

Answer 11

Flecainide

Propafenone

Question 12

Class 1C Medication ADRs

Answer 12

Propafenone:
Metallic taste
Constipation

Question 13

Class II Medications

Answer 13

Beta Blockers
Propranolol
Metoprolol
Atenolol

Question 14

Class III Medications

Answer 14

Sotalol
Ibutilide
Amiodarone

Question 15

Class IV Medications

Answer 15

Adenosine
Magnesium
Potassium
Digoxin

Question 16

Amiodarone ADRs

Answer 16

Hepatitis
Gray-blue skin discoloration
Blindness

Question 17

Quinidine Clinical Uses

Answer 17

Atrial flutter and afib

Ventricular arrhythmia

Question 18

Procainamide and Disopyramide Clinical Uses

Answer 18

Ventricular arrhythmias

Question 19

Lidocaine Clinical Uses

Answer 19

Ventricular arrhythmias - first line

Question 20

Sotalol Clinical Uses

Answer 20

Ventricular arrhythmias
Afib
Arrhythmias in pediatrics

Question 21

Ibutilide Clinical Uses

Answer 21

Acute conversion of atrial flutter or afib to normal sinus rhythm

Question 22

Amiodarone Clinical Uses

Answer 22

Wolff Parkinson arrhythmias
Afib
Ventricular arrhythmias

Question 23

Adenosine Clinical Uses

Answer 23

Paroxysmal supraventricular tachycardia

Question 24

Magnesium Clinical Uses

Answer 24

Sinus tachycardia
Torsade de pointe
Digitalis induced arrhythmias

Question 25

Medications that may worsen HF

Answer 25

NSAIDs
CCBs
Sotalol

Question 26

ARNI (HF)

Answer 26

Sacubitril/Valsartan

Question 27

Sacubitril/Valsartan ADRs

Answer 27

Hypotension
Hyperkalemia
Renal Failure

Question 28

HCN Channel Inhibitor (HF)

Answer 28

Ivabradine

Question 29

Ivabradine ADRs

Answer 29

Bradycardia
Afib
Visual brightness

Question 30

Loop Diuretics (HF)

Answer 30

Furosemide
Torsemide
Bumetanide

Question 31

Potassium Supplements and ADRs

Answer 31

Acetate, bicarbonate, chloride

N/V/D

Question 32

Sodium Polystyrene Sulfonate (HF)

Answer 32

Used for hyperkalemia

Kayexalate

Question 33

Kayexalate ADRs

Answer 33

N/V, constipation

Question 34

Stage D Medications (HF)

Answer 34

Dopamine
Dobutamine
Milirinone

Question 35

Cardiac Glycosides

Answer 35

Digoxin
Digitoxin
Digitalis
Oleander

Question 36

Digoxin ADRs

Answer 36

Hypotension
Arrhythmias
Bradycardia

Question 37

Vasodilators

Answer 37

Nitrates
Hydralazine
Minoxidil

Question 38

Prostanoids (Pulm. HTN)

Answer 38

Epoprostenol
Treprostinil
Iloprost

Question 39

Prostanoids ADRs

Answer 39

N/V, dizziness

Question 40

Endothelin Receptor Antagonists (Pulm HTN)

Answer 40

Bosentan

Ambrisentan

Question 41

PDE 5 Inhibitors (Pulm HTN)

Answer 41

Sildenafil

Tadalafil

Question 42

PDE 5 Inhibitor ADRs

Answer 42

Hypotension, priapism, vision/hearing loss