Antiarrhythmics/Heart Failure Flashcards

1
Q

Class IA Overview

A

Increases AP Duration (lengthens)

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2
Q

Class 1B Overview

A

Shorten duration of AP and refractory period

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3
Q

Class 1C Overview

A

No or little effect on the duration of AP or refractory period

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4
Q

Class II

A

B-adrenoceptor blocker

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5
Q

Class III

A

K+ channel blockers

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6
Q

Class IV

A

Ca 2+ channel blockers

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7
Q

Class 1A Medications

A

Quinidine
Procainamide
Disopyramide

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8
Q

Class 1A Medication ADR

A

Prolonged QT Interval
Induction of torsades de pointes
Nausea

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9
Q

Class 1B Medications

A

Lidocaine

Mexiletine

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10
Q

Class 1B Medications ADR

A

Hypotension
Tremor
Lightheadedness

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11
Q

Class 1C Medications

A

Flecainide

Propafenone

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12
Q

Class 1C Medication ADRs

A

Propafenone:
Metallic taste
Constipation

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13
Q

Class II Medications

A

Beta Blockers
Propranolol
Metoprolol
Atenolol

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14
Q

Class III Medications

A

Sotalol
Ibutilide
Amiodarone

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15
Q

Class IV Medications

A

Adenosine
Magnesium
Potassium
Digoxin

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16
Q

Amiodarone ADRs

A

Hepatitis
Gray-blue skin discoloration
Blindness

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17
Q

Quinidine Clinical Uses

A

Atrial flutter and afib

Ventricular arrhythmia

18
Q

Procainamide and Disopyramide Clinical Uses

A

Ventricular arrhythmias

19
Q

Lidocaine Clinical Uses

A

Ventricular arrhythmias - first line

20
Q

Sotalol Clinical Uses

A

Ventricular arrhythmias
Afib
Arrhythmias in pediatrics

21
Q

Ibutilide Clinical Uses

A

Acute conversion of atrial flutter or afib to normal sinus rhythm

22
Q

Amiodarone Clinical Uses

A

Wolff Parkinson arrhythmias
Afib
Ventricular arrhythmias

23
Q

Adenosine Clinical Uses

A

Paroxysmal supraventricular tachycardia

24
Q

Magnesium Clinical Uses

A

Sinus tachycardia
Torsade de pointe
Digitalis induced arrhythmias

25
Medications that may worsen HF
NSAIDs CCBs Sotalol
26
ARNI (HF)
Sacubitril/Valsartan
27
Sacubitril/Valsartan ADRs
Hypotension Hyperkalemia Renal Failure
28
HCN Channel Inhibitor (HF)
Ivabradine
29
Ivabradine ADRs
Bradycardia Afib Visual brightness
30
Loop Diuretics (HF)
Furosemide Torsemide Bumetanide
31
Potassium Supplements and ADRs
Acetate, bicarbonate, chloride | N/V/D
32
Sodium Polystyrene Sulfonate (HF)
Used for hyperkalemia | Kayexalate
33
Kayexalate ADRs
N/V, constipation
34
Stage D Medications (HF)
Dopamine Dobutamine Milirinone
35
Cardiac Glycosides
Digoxin Digitoxin Digitalis Oleander
36
Digoxin ADRs
Hypotension Arrhythmias Bradycardia
37
Vasodilators
Nitrates Hydralazine Minoxidil
38
Prostanoids (Pulm. HTN)
Epoprostenol Treprostinil Iloprost
39
Prostanoids ADRs
N/V, dizziness
40
Endothelin Receptor Antagonists (Pulm HTN)
Bosentan | Ambrisentan
41
PDE 5 Inhibitors (Pulm HTN)
Sildenafil | Tadalafil
42
PDE 5 Inhibitor ADRs
Hypotension, priapism, vision/hearing loss