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CRP > Antianemic Agents > Flashcards

Antianemic Agents Flashcards

1
Q

Types of Anemias

A
  • Normocytic- mean cell volume (MCV) 80-99fL
  • Microcytic- MCV < 80 fL (iron deficiency)
  • Macrocytic- MCV > 100 fL (folic acid and/or vit. B12 deficiency)
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2
Q

Iron Deficiency Anemia Treatment Goals

A
  • Restore hemoglobin synthesis and RBC production
  • Replenish ferritin and hemosiderin stores
  • Drugs: ferrous sulfate, iron dextran injection
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3
Q

Iron Deficiency Anemia Treatment Adverse Effects

A
  • GI
  • Hemosiderosis/hemochromatosis
  • Acute toxicity
  • Treatment: deferoxamine
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4
Q

Folic Acid Metabolic Role Illustration

A
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5
Q

Hematopoietic Growth Factors

A
  • Erythropoietin; used in chronic renal failure and anemia of chronic disease
  • Filgrastim (G-CSF); used in recovery from chemotherapy; mobilizes hematopoietic blood cells in the hematopoeitic stem cell transplantation
  • Sargramostim (GM-CSF); used in recovery of chemotherapy/bone marrow transplantation
  • Oprelvekin (IL-ll); used in thrombocytopenia that may result from chemotherapy
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