Anti Virals

Question 1

Metronidazole

Answer 1

1st line treatment in C. difficile colitis
Treatment of H. pylori and dental infections
Used for anaerobic cover in intra-abdominal sepsis

Anti-protozoal agent and has good
anaerobic cover and effective against clostridia.

GI disturbance: nausea & vomiting

• Metallic taste in mouth
• Dizziness, headache
• Reaction when taken with alcohol → Vomiting

Question 2

Aciclovir and Famciclovir

Answer 2

Treatment of HSV: -Topical
Treatment of VZV: -Oral, higher doses than for HSV. Shortens duration and number of lesions.
-Genital herpes

GI upset: Nausea

• Headache
• Reduce doses in renal impairment
• Nephrotoxicity & Neurotoxicity in large IV doses

Question 3

Osteltamivir

Answer 3

Influzena
*Tamiflu has no real reduction of complications in normal patients, but worked for pregnant women and the immunocompromised.

GI disturbances

• Dizziness, headache
• Nosebleeds
• Eye discomfort/redness