Anti-thyroid drugs ( Carbimazole) Flashcards
1
Q
What is the drug class of carbimazole?
A
Thioamides (antithyroid agent)
2
Q
How does carbimazole work to treat hyperthyroidism?
A
Carbimazole works by preventing the thyroid peroxidase enzyme from producing T3 / T4
3
Q
What groups of patients should carbimazole be used with caution?
A
- liver disease
- pregnancy and breastfeeding
4
Q
What are the side effects of carbimazole?
A
GI upset - nausea, vomiting headache skin rash itching bone marrow supression (rare)
5
Q
What are the possible drug interactions of carbimazole?
A
Warfarin
6
Q
Why should carbimazole be used with caution in the elderly?
A
it is associated with higher risk of fatal blood disorders in the elderly.
