Anti-thrombotic

Question 1

Examples of antiplatelets

Answer 1

Aspirin, clopidogrel, ticagrelor, prasugrel

Question 2

What do antiplatelets do

Answer 2

Prevent new thrombosis

Question 3

When are antiplatelets used

Answer 3

Angina, acute MI, CVA and TIA

Question 4

Side effects of antiplatelets

Answer 4

Haemorrhage, peptic ulcer haemorrhage and aspirin sensitive asthma

Question 5

Give examples of anticoagulents

Answer 5

Warfarin

Question 6

What does warfarin do

Answer 6

Prevents new thrombosis by blocking clotting factor 2, 7, 9 and 10

Question 7

When is warfarin used

Answer 7

DVT, PE, NSTEMI and atrial fibrillation

Question 8

Side effects of warfarin

Answer 8

Haemorrhage

Question 9

What factor is inhibited by rivaroxaban

Answer 9

Factor 10a

Question 10

What factor is inhibited by dabigatran

Answer 10

Thrombin factor 2a inhibitor

Question 11

Name a fibrinolytic

Answer 11

Streoptokinase

Question 12

What does streptokinase do

Answer 12

Dissolves formed clots

Question 13

When is streptokinase used

Answer 13

STEMI, PE (rarely) and CVA (rarely)

Question 14

Side effects of streptokinase

Answer 14

Avoid in recent haemorrhae, trauma and bleeding tendancies