Anti-platelet Flashcards

1
Q

vWF (receptor)

A

Receptor: GP 1b-IX-V
No pharmacological inhibitor

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2
Q

Collagen (receptor)

A

Receptor: GPVI
No pharmacological inhibitor

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3
Q

Fibrinogen/fibrin

A

Receptor: Integrin aIIbB3

Pharmacological inhibitor:
Abciximab
Eptifibatide

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4
Q

ADP

A

Receptor: P2Y1
G-protein family: Gq
Pharm Inhibitor: Clopidogrel

Receptor: P2Y12
G-protein family: Gi
Pharm inhibitor: Prasugrel

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5
Q

Thromboxane

A

Receptor: TXA2R
G-protein family: Gq
Pharm inhibitor: Aspirin

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6
Q

Thrombin

A

Receptors: PAR1, PAR4
G-protein family: Gq, G12
Pharm inhibitor: In development (atopaxar)

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