Anti-platelet Flashcards
1
Q
vWF (receptor)
A
Receptor: GP 1b-IX-V
No pharmacological inhibitor
2
Q
Collagen (receptor)
A
Receptor: GPVI
No pharmacological inhibitor
3
Q
Fibrinogen/fibrin
A
Receptor: Integrin aIIbB3
Pharmacological inhibitor:
Abciximab
Eptifibatide
4
Q
ADP
A
Receptor: P2Y1
G-protein family: Gq
Pharm Inhibitor: Clopidogrel
Receptor: P2Y12
G-protein family: Gi
Pharm inhibitor: Prasugrel
5
Q
Thromboxane
A
Receptor: TXA2R
G-protein family: Gq
Pharm inhibitor: Aspirin
6
Q
Thrombin
A
Receptors: PAR1, PAR4
G-protein family: Gq, G12
Pharm inhibitor: In development (atopaxar)