Anti PARKINSON’S DISEASE

Question 1

What is drugs that diminishes the metabolism of levodopa in the periphery?

Answer 1

a dopamine decarboxylase inhibitor that does not cross the blood–brain barrier.
Carbidopa, a dopamine decarboxylase inhibitor,
diminishes the metabolism of levodopa in the periphery., thereby increasing the availability of levodopa to the CNS. The addition of carbidopa lowers the dose of levodopa needed by four- to five-fold and, consequently, decreases the severity of adverse effects arising from peripherally formed dopamin

Question 2

On any receptor NOTE:
1 Dopamine receptors exist in five subtypes. D1 and D5 receptors. The benefits of dopaminergic anti-parkinsonism drugs appear ? and on any receptor appear maximal benefit of dopaminergic anti-parkinsonism?

Answer 2

Dopamine receptors exist in five subtypes. D1 and D5 receptors. The benefits of dopaminergic anti-parkinsonism drugs appear to depend mostly on stimulation of the D2 receptors. However, D3- receptor stimulation may also be required for maximal benefit and one of the newer drugs is D3 selective.

Question 3

What is name Levodopa and Carbidopa together?

Answer 3

Sinemet

Question 4

What are drugs of DOPAMINE RECEPTOR AGONISTS?

Answer 4

🌸Bromocriptine
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🌸pergolide
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🌸Ropinirole
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🌸pramipexol
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