Anti microbial cheomotherapy

Question 1

substance of microbial naturally produced which kill or inhibit the growth for other organisms

Answer 1

antibiotics

Question 2

treatment of infectious diseases by taking drug that inhibit the causative organisms

Answer 2

antimicrobial chemotherapy

Question 3

chemical agents that non toxic to living tissue

Answer 3

antiseptics

Question 4

they can br applied on human skin with out beeing harmful but harm the systemic adminstration

Answer 4

antiseptics

Question 5

destruction of most pathogenic microbes eg phenol

Answer 5

disinfection

Question 6

rapid killing of bacteria which is irreversible

Answer 6

bactericidal drugs

Question 7

usage of bactericidal

Answer 7

life threatening diseases eg
endocarditis

Question 8

examples of bactericidal drugs

Answer 8

penicillins, cephalosporins, and aminoglycosides

Question 9

inhibit the multiplication of bacteria but do not kill them

Answer 9

bacteriostatic drug

Question 10

bacteria back again when drug is withdrawn

Answer 10

bacteriostatic drug

Question 11

Eg of bacteriostatic drug

Answer 11

sulphonamides
tetracyclins
chloramphenicole

Question 12

affective against several microorganisms include gram postive and negative

Answer 12

broad spectrum antibiotics

Question 13

eg broad spectrum antibiotics

Answer 13

tetracyclins
chloramphenicole
ampicillins

Question 14

active against only one or few types of microorganisms

Answer 14

narrow spectrum antibiotics

Question 15

used against gram postive cocci and staphylocci and entrococci

Answer 15

vancomycin (narrow spectrum )

Question 16

Properties of an Ideal Antimicrobial Agent:

Answer 16

Selective toxicity:
Broad spectrum:
Bactericidal agents
Diffusible
bacteria do not develop resistance to it

Question 17

define Broad spectrum:

Answer 17

affect wide variety of bacteria

Question 18

Bactericidal agents

Answer 18

killing better than inhibit

Question 19

Diffusible

Answer 19

into distant area with slow rate of excretion

Question 20

selective toxicity

Answer 20

harmful to the parasite without ben=ing harmful to the host

Question 21

mechanisms of action of chemotherapeutics drugs

Answer 21

inhibit the metabolic channels or a structure present in microbe

Question 22

what is the ideal point of attack by selective toxic agents

Answer 22

cell wall

Question 23

drugs that inhibit cell wall synthesis

Answer 23

B lactims drugs

Question 24

ex of B lactims drugs

Answer 24

penicillin, methicillin and cephalosporins

Question 25

what is the importance of vancomycin

Answer 25

used in tratment of B-lactam resistant stephylococcal infections (MRSA)

Question 26

inhibit peptidoglycan synthesis

Answer 26

vancomycin q

Question 27

why certain drugs inhibits bactreial protein synthesis without inhibits human

Answer 27

differences between human and bacterial ribosomes in human it is 80 and bacteria it is 70

Question 28

these drugs act on what ribosome erythromycin
chloramphenicol

Answer 28

acto on 50s

Question 29

these drugs act on what ribosome?
amino glycosides (gentamicin and amikin)
tetracycline

Answer 29

act on 30

Question 30

sulphonoamides

Answer 30

inhibits folic acids synthesis

Question 31

the mechanisms bacteria can develop resistance to drugs

Answer 31

production of enzymes
synthesis modified targets

Question 32

inactivate penicilin and cephalosporing

Answer 32

B lactimase

Question 33

inhibition of bacterial nucleic acid synthesis

Answer 33

Quinolones
Rifampicin

Question 34

what is the function of Quinolones
and how ?

Answer 34

inhibit DNA synthesis
by blocking DNA gyrase

Question 35

what is the function of Rifampcin
and how ?

Answer 35

inhibit RNA synthesis
by blocking RNA polymerase