Anti- Inflammatory

Question 1

HYDROCORTISONE

Cortef, Solu-Cortef

Answer 1

Corticosteroids
Treatment of severe inflammation, septic shock, adrenal insufficiency, ulcerative colitis, collagen disorders
Check for elevated temp, WBC count
PO: Take with food, milk, antacids
IM: Give deep in gluteal, avoid deltoid, rotate sites, avoid subq
Monitor blood sugars
Rectal: retain med for 20 minutes, onset 3-5 days
Wear med tag
Do not mix with other medications
Preg Cat C

Side Effects:
Depression, flushing, sweating, HTN, Nausea, diarrhea, hyperglycemia, psychic derangements

Question 2

METHYLPREDNISOLONE

Medrol

Answer 2

Corticosteroids
Treatment of severe inflammation, shock, adrenal insufficiency, management of acute spinal cord injury, collagen disorders
PO: Take w/ food, milk, antacids, peak 1-2 hr, duration 1.5 days
IM: Deep in gluteal, Avoid deltoid and subq, peak 4-8 days, duration 1-4 week
Eat foods high in protein, CA, Vit D, AVOID Sodium
Contact Dr: anorexia, difficulty breathing, weakness, dizziness
Contact Dr: Black, tarry stool, slow wound healing, blurred vision bruising, bleeding, weight gin, emotional changes
Wear medical tag
Monitor weight and blood sugars
Preg Cat C

Side Effects:
Peptic ulcers, possible perforation, HTN, circulatory problems, poor wound healing, hyperglyemica, psychic derangements

Question 3

PREDNISOLONE

Delta-Cortef, Flo-Pred, PRed Forte, Prelone

Answer 3

Corticosteroids
Treatment of severe inflammation, immunosuppression, neoplasms
PO: Take with food, milk, antacids, peak 1-2hr, lasts 3-36hr
IM: Deep in gluteal, Avoid deltoid and subq, peak 1 hr, lasts 4 weeks
Eat food high in protein, Ca, Vit D, Avoid Sodium
Contact Dr: Black, tarry stool, slow wound healing, blurred vision bruising, bleeding, weight gin, emotional changes, anorexia, difficulty breathing, weakness, dizziness
Wear medical tag
Preg Cat C

Side Effects:
Depression, HTN, Circulatory problems, Nausea, Diarrhea, abdominal distension

Question 4

PREDNISONE

Deltasone, Meticorten

Answer 4

Corticosteroids
Treatment of severe inflammaion, immune suppression, neoplasms, multiple sclerosis, collagen disorders, dermatological disorders, myasthenia gravis
PO: Take with food, milk, antacids, peak 1-2hr, lasts 24-36hr
Eat food high in protein, Ca, Vit D, Avoid Sodium
Contact Dr: Black, tarry stool, slow wound healing, blurred vision bruising, bleeding, weight gin, emotional changes
Excessive licorice and increase Hypokalemia
Wear medical tag
Monitor blood sugars
Preg Cat C

Side Effects:
Peptic Ulcer, perforation
Depression, HTN, circulatory issues, Nausea, Diarrhea, Abdominal distention, Hyperglycemia, Psychic derangement

Question 5

NABUMETONE

Answer 5

NSAID
Used to manage symptoms of osteoarthritis and rheumatoid arthritis
Take w/ food or milk
Contraindicated with hypersensitivity to other NSAIDs
Alcohol can increase ulcerogenic effects
May take 2 weeks to notice improvement
Preg Cat C

Side Effects:
Abdominal pain, constipation, diarrhea, gas, tinnitus, edema, HA, Rash, gastritis

Question 6

IBUPROFEN

Advil, Motrin

Answer 6

NSAID
Treatment of rheumatoid arthritis, osteoarthritis, primary dysmenorrhea, gout, dental pain, musculoskeletal disorders, fever, HA, menstrual cramps
Onset 30min, peak 1-2hr
Full effect may take 1 mo
Contact Dr: Blurred vision, ringing or roaring in ears (Toxicity)
Contact Dr: change in urinary pattern, increased weight, edema, increased joint pain, fever, blood in urine (Kidney damage)
Avoid use with ASA, NSAIDs, Alcohol
Take with food or milk
Possible cross allergy with aspirin
Preg Cat C

Side Effects:
HA, Nausea, Anorexia, GI bleeding, Blood dyscrasias, Hives, Facial swelling, Rash

Question 7

NAPROXEN

Aleve, Anaprox, Naprosyn

Answer 7

NSAID
Management of mild to moderate pain, treatment of rheumatoid juvenile, gouty arthritis, osteoarthritis, primary dysmenorrhea
High risk with asthma, ASA hypersensitivity, nasal polyps
Contact Dr: Blurred vision, ringing or roaring in ears (Toxicity)
Contact Dr: change in urinary pattern, increased weight, edema, increased joint pain, fever, blood in urine (Kidney damage)
Contact Dr: black stools, flulike symptoms
Use sunscreen to prevent photo-sensitivity
Avoid ASA, Steroids, Alcohol
Preg Cat C

Side Effects:
GI Bleeding, Blood Dyscrasias, Hives, Rash, Asthma