Anti-Infectives/Antibiotics Flashcards
what are some of the body’s defenses toward infection?
physical barriers; physiologic defenses; phagocytic cells
what are the signs of infection?
fever, lethargy, slow-wave sleep induction, classic signs of inflammation (redness, swelling, heat, and pain)
what is the goal of antiinfective therapy?
reduction of the population invading the organism
immune response
a complex process involving chemical mediators, leukocytes, antibodies, and locally released enzymes and chemicals
narrow spectrum antibiotics
effective against only a few microorganisms with a very specific metabolic pathway or enzyme
broad spectrum antibiotics
useful in treating a wide variety of infections
empiric therapy
treatment of an infection before a specific culture information has been reported or obtained
definitive therapy
therapy tailored to treat organism identified with cultures
prophylactic therapy
prevent infection
therapeutic response
decrease in specific signs and symptoms of infection are noted (fever, elevated WBC count, redness, inflammation, drainage, pain)
subtherapeutic response
signs and symptoms of infection don’t imporve
what are common antibiotics that give allergic reactions
penicillins and sulfonamides
what is a severe reaction
difficulty breathing; significant rash, hives, or skin reaction; GI intolerance; anaphylaxis
signs and symptoms of c. diff
water diarrhea, abdominal cramps, pain/tenderness, fever, pus/mucus in stool, nausea, dehydration
what are some nursing implications for antibiotics?
assess all lab results, medications, allergies, and patient profile; administer on a schedule and take full course