Anti-HTN meds

Question 1

B1/B2 Blocker

Answer 1

Propanolol

Question 2

Indication for Propanolol

Answer 2

Angina, 
HTN, 
Essential tremor, 
migraine Px, 
anxiety

Question 3

Contraindications for Propanolol

Answer 3

Bradycardia
Heart block
Uncompensated HF
Severe depression
Bronchospams

Question 4

Propanolol caution in elderly

Answer 4

2x the potency

Question 5

Selective B1 Blocker

Answer 5

Metropolol

Atenolol

Question 6

Indication for Metropolol

Answer 6

Angina
HTN
Stable post MI

Question 7

Contraindications for Metropolol

Answer 7

Bradycardia
Heart block
Uncompensated HF
Severe depression

Question 8

What do high doses of Metrolpolol and Atenolol do

Answer 8

Lose selectivity

Question 9

Alpha 1 blocker

Answer 9

Prazosin

Question 10

Prazosin MOA

Answer 10

Selective A1 blocker relaxes vascular smooth muscle

Question 11

Indications for Prazosin

Answer 11

HTN

PTDS, Reynauds

Question 12

Side effects of Prazosin

Answer 12

Postural HOTN

Syncope

Question 13

Contraindications for Prazosin

Answer 13

Orthostatic HOTN

Question 14

Prazosin Dx-Dx interaction

Answer 14

PDE-5 inhibitors

Other anti-HTNs

Question 15

Centrally acting Alpha 2 AGONIST

Answer 15

Clonidine

Methyldopa

Question 16

What is Methyldopa indicated for?

Answer 16

Hypertensive crisis in pregnancy

Question 17

Indications for Clonidine

Answer 17

HTN
ADHD
Narc, ETOH w/d

Question 18

Clonidine side effect

Answer 18

Xerostoma

Question 19

Contraindications for Clonidine

Answer 19

CNS depression

Severe CAD

Question 20

Clonidine Dx-Dx interaction

Answer 20

ETOH, SA/AVN altering drugs

Question 21

B1/B2/A1 blocker

Answer 21

Carvedolol

Question 22

Indications for Carvedolol

Answer 22

HTN
Stable post MI
(Angina)

Question 23

Carvedolol side effects

Answer 23

Rebound HTN/angina

Question 24

Contraindications for Carvedolol

Answer 24

Bradycardia
Heart block
Uncompensated HF
Severe depression
Broncospasm
Liver Dz

Question 25

Name the Bet Blockers

Answer 25

Metropolol Atenolol Propanolol Carvedolol

Question 26

Name the Alpha2 agonists

Answer 26

Clonidine | Methyldopa

Question 27

ACEIs

Answer 27

Lisinopril Captopril Fosinopril

Question 28

ACEI MOA

Answer 28

Inhibits conversion of AT1 into AT, decreasing vasoconstriction and aldosterone secretion

Question 29

Indication for ACEI

Answer 29

HTN HF LVD post MI

Question 30

Side effects of ACEI

Answer 30

Cough | Angioedema

Question 31

Contraindications for ACEI

Answer 31

Hx of angioedema pregnancy bilateral renal artery stenosis

Question 32

What drugs don;t we mix with ACEIs?

Answer 32

ARBs | Aliskerin

Question 33

When do we modify the dose of ACEI?

Answer 33

Renal Dz

Question 34

What do we watch for with the first dose of an ACEI?

Answer 34

HOTN

Question 35

Angiotensin Receptor Blocker (ARB)

Answer 35

Losartan

Question 36

What does Losartan primarily bind to?

Answer 36

AT1

Question 37

What don;t we use in combo with ARBs?

Answer 37

ACEIs | Aliskerin

Question 38

Direct Renin Inhibitor

Answer 38

Aliskerin

Question 39

Aliskerin MOA

Answer 39

Direct renin inhibitor vasodilates

Question 40

Indication for Aliskerin

Answer 40

HTN

Question 41

What drugs do we avoid when on Aliskerin?

Answer 41

ACEIs | ARBs

Question 42

What else do we avoid on Aliskerin?

Answer 42

Grapefruit juice

Question 43

Two DHP Calcium Channel Blockers

Answer 43

Amplodipine | Nifedipine

Question 44

Indications for DHP CCBs

Answer 44

HTN | Chronic stable or vasospastic angina

Question 45

Side effect of Amlodipine

Answer 45

Dependent edema

Question 46

Side effect of Nifedipine

Answer 46

HOTN, esp in elderly

Question 47

What do we avoid when on DHP CCBs?

Answer 47

Grapefruit juuice

Question 48

Two NDHP Calcium Chanel Blockers

Answer 48

Diltiazem | Verapamil

Question 49

NDHP CCB MOA

Answer 49

Dilates coronary arteries and decreased MVO2

Question 50

Indications for NDHP CCBs

Answer 50

Angina HTN A-fib/flutter

Question 51

Side effect of Diltiazem

Answer 51

Dyspepsia

Question 52

Side effect of Verapamil

Answer 52

Gingival hyperplasia

Question 53

Contraindications for NDHP CCBs

Answer 53

Bradycardia | Sick sinus syndrome without a pacer

Question 54

What do we avoid with NHDP CCBs?

Answer 54

Grapefruit juice

Question 55

Direct-acting Vasodilator

Answer 55

Hydralazine

Question 56

What does Hydralazine dilate?

Answer 56

Arterioles

Question 57

Indications for Hydralazine

Answer 57

Hypertensive crisis | (pre) eclampsia

Question 58

What condition does Hydralazine CAUSE?

Answer 58

Lupus

Question 59

Contraindications for Hydralazine

Answer 59

CAD | Mitral Valve rheumatic heart dz

Question 60

Thiazide diuretic

Answer 60

HCTZ

Question 61

Where does HCTZ inhibit Na+/Cl- symporters?

Answer 61

Distal convoluted tubule

Question 62

Indications for HCTZ

Answer 62

HTN Edema of nephrotic syndrome (Lithium-induced diabetic insipidus)

Question 63

Side effects of HCTZ

Answer 63

Hypokalemia | Long QT

Question 64

Contraindication of HCTZ

Answer 64

Sulfa allgery

Question 65

HCTZ Dx-Dx interactions

Answer 65

Beta blockers, Lithium, NSAIDs

Question 66

Chlorthalodone class

Answer 66

Thiazide-like diuretic

Question 67

How much more potent is Clorthalodoe than HCTZ?

Answer 67

2X

Question 68

K+ sparing diuretic

Answer 68

Triamterene

Question 69

Triamterene indication

Answer 69

Hypokalemia

Question 70

Contraindication of Triamterene

Answer 70

Sulfa allergy

Question 71

Triamterene Dx-Dx interactions

Answer 71

Other K+ sparing drugs

Question 72

What do we usually combine Triamtere with?

Answer 72

Thiazide diuretics