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CV 2 meds > Anti-HTN meds > Flashcards

Anti-HTN meds Flashcards

1
Q

B1/B2 Blocker

A

Propanolol

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2
Q

Indication for Propanolol

A 
Angina, 
HTN, 
Essential tremor, 
migraine Px, 
anxiety
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3
Q

Contraindications for Propanolol

A 
Bradycardia
Heart block
Uncompensated HF
Severe depression
Bronchospams
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4
Q

Propanolol caution in elderly

A

2x the potency

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5
Q

Selective B1 Blocker

A

Metropolol

Atenolol

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6
Q

Indication for Metropolol

A

Angina
HTN
Stable post MI

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7
Q

Contraindications for Metropolol

A

Bradycardia
Heart block
Uncompensated HF
Severe depression

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8
Q

What do high doses of Metrolpolol and Atenolol do

A

Lose selectivity

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9
Q

Alpha 1 blocker

A

Prazosin

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10
Q

Prazosin MOA

A

Selective A1 blocker relaxes vascular smooth muscle

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11
Q

Indications for Prazosin

A

HTN

PTDS, Reynauds

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12
Q

Side effects of Prazosin

A

Postural HOTN

Syncope

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13
Q

Contraindications for Prazosin

A

Orthostatic HOTN

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14
Q

Prazosin Dx-Dx interaction

A

PDE-5 inhibitors

Other anti-HTNs

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15
Q

Centrally acting Alpha 2 AGONIST

A

Clonidine

Methyldopa

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16
Q

What is Methyldopa indicated for?

A

Hypertensive crisis in pregnancy

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17
Q

Indications for Clonidine

A

HTN
ADHD
Narc, ETOH w/d

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18
Q

Clonidine side effect

A

Xerostoma

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19
Q

Contraindications for Clonidine

A

CNS depression

Severe CAD

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20
Q

Clonidine Dx-Dx interaction

A

ETOH, SA/AVN altering drugs

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21
Q

B1/B2/A1 blocker

A

Carvedolol

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22
Q

Indications for Carvedolol

A

HTN
Stable post MI
(Angina)

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23
Q

Carvedolol side effects

A

Rebound HTN/angina

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24
Q

Contraindications for Carvedolol

A 
Bradycardia
Heart block
Uncompensated HF
Severe depression
Broncospasm
Liver Dz
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25
Q

Name the Bet Blockers

A

Metropolol
Atenolol
Propanolol
Carvedolol

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26
Q

Name the Alpha2 agonists

A

Clonidine

Methyldopa

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27
Q

ACEIs

A

Lisinopril
Captopril
Fosinopril

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28
Q

ACEI MOA

A

Inhibits conversion of AT1 into AT, decreasing vasoconstriction and aldosterone secretion

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29
Q

Indication for ACEI

A

HTN
HF
LVD post MI

30
Q

Side effects of ACEI

A

Cough

Angioedema

31
Q

Contraindications for ACEI

A

Hx of angioedema
pregnancy
bilateral renal artery stenosis

32
Q

What drugs don;t we mix with ACEIs?

A

ARBs

Aliskerin

33
Q

When do we modify the dose of ACEI?

A

Renal Dz

34
Q

What do we watch for with the first dose of an ACEI?

A

HOTN

35
Q

Angiotensin Receptor Blocker (ARB)

A

Losartan

36
Q

What does Losartan primarily bind to?

A

AT1

37
Q

What don;t we use in combo with ARBs?

A

ACEIs

Aliskerin

38
Q

Direct Renin Inhibitor

A

Aliskerin

39
Q

Aliskerin MOA

A

Direct renin inhibitor vasodilates

40
Q

Indication for Aliskerin

A

HTN

41
Q

What drugs do we avoid when on Aliskerin?

A

ACEIs

ARBs

42
Q

What else do we avoid on Aliskerin?

A

Grapefruit juice

43
Q

Two DHP Calcium Channel Blockers

A

Amplodipine

Nifedipine

44
Q

Indications for DHP CCBs

A

HTN

Chronic stable or vasospastic angina

45
Q

Side effect of Amlodipine

A

Dependent edema

46
Q

Side effect of Nifedipine

A

HOTN, esp in elderly

47
Q

What do we avoid when on DHP CCBs?

A

Grapefruit juuice

48
Q

Two NDHP Calcium Chanel Blockers

A

Diltiazem

Verapamil

49
Q

NDHP CCB MOA

A

Dilates coronary arteries and decreased MVO2

50
Q

Indications for NDHP CCBs

A

Angina
HTN
A-fib/flutter

51
Q

Side effect of Diltiazem

A

Dyspepsia

52
Q

Side effect of Verapamil

A

Gingival hyperplasia

53
Q

Contraindications for NDHP CCBs

A

Bradycardia

Sick sinus syndrome without a pacer

54
Q

What do we avoid with NHDP CCBs?

A

Grapefruit juice

55
Q

Direct-acting Vasodilator

A

Hydralazine

56
Q

What does Hydralazine dilate?

A

Arterioles

57
Q

Indications for Hydralazine

A

Hypertensive crisis

(pre) eclampsia

58
Q

What condition does Hydralazine CAUSE?

A

Lupus

59
Q

Contraindications for Hydralazine

A

CAD

Mitral Valve rheumatic heart dz

60
Q

Thiazide diuretic

A

HCTZ

61
Q

Where does HCTZ inhibit Na+/Cl- symporters?

A

Distal convoluted tubule

62
Q

Indications for HCTZ

A

HTN
Edema of nephrotic syndrome
(Lithium-induced diabetic insipidus)

63
Q

Side effects of HCTZ

A

Hypokalemia

Long QT

64
Q

Contraindication of HCTZ

A

Sulfa allgery

65
Q

HCTZ Dx-Dx interactions

A

Beta blockers, Lithium, NSAIDs

66
Q

Chlorthalodone class

A

Thiazide-like diuretic

67
Q

How much more potent is Clorthalodoe than HCTZ?

A

2X

68
Q

K+ sparing diuretic

A

Triamterene

69
Q

Triamterene indication

A

Hypokalemia

70
Q

Contraindication of Triamterene

A

Sulfa allergy

71
Q

Triamterene Dx-Dx interactions

A

Other K+ sparing drugs

72
Q

What do we usually combine Triamtere with?

A

Thiazide diuretics

CV 2 meds (3 decks)

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