Anti-dysrhythmia meds

Question 1

Class 1a Sodium Channel Blocker

Answer 1

Procainamide

Question 2

Procainamide MOA

Answer 2

Increases electrical threshold, decreasing myocardial excitability and conduction velocity

Question 3

Indication for Procainamide

Answer 3

Ventricular dysrythmias

Question 4

Procainamide side effect

Answer 4

SLE

Question 5

Contraindications for Procainamide

Answer 5

SLE, high degree heart block, Torsades

Question 6

When should we adjust the dose of Procainamide?

Answer 6

Renal and hepatic impairment

Question 7

Class 1b Sodium Channel Blocker

Answer 7

Lidocaine

Question 8

Lidocaine MOA

Answer 8

Decreases automaticity by increasing threshold

Question 9

Indication for Lidocaine

Answer 9

Ventricular dysrhythmias

Question 10

Lidocaine side effect

Answer 10

Increased defib threshold

Question 11

Contraindications for Lidocaine

Answer 11

Heart block without pacer

Corn allergy

Question 12

Lidocaine PG category

Answer 12

B

Question 13

Class 1c Sodium Channel Blocker

Answer 13

Flecainide

Question 14

Flecainide MOA

Answer 14

Alters ion transport across membranes, slowing cardiac conduction and increasing refractory periods

Question 15

Indications for Flecainide

Answer 15

SVT, ventricular dysrhythmias, A-fib/fluter

Question 16

Contraindications for Flecainide

Answer 16

High degree heart block
RBBB
Cardiogenic shock

Question 17

Is Flecainide indicated for chronic A-fib?

Answer 17

No

Question 18

What are the Class 2 anti-dysrhythmias?

Answer 18

Beta blockers

Question 19

Nonspecific BB

Answer 19

Propanolol

Question 20

Cardiospecific BB

Answer 20

Atenolol

Metoprolol

Question 21

Class 3 anti-dysrhythmic

Answer 21

Amiodarone

Question 22

Amiodarone MOA

Answer 22

Inhibits alpha/beta adrenergic stimulation, prolonging AP and refractory periods, decreasing SA/AVN conduction

Question 23

Indications for Amiodarone

Answer 23

VF, Refractory VT (SVT, A_fib)

Question 24

Amiodarone side effects

Answer 24

Pulm toxicity

Question 25

Contraindications for Amiodarone

Answer 25

Iodine allergy
cardiogenic shock
High heart block
SAN dysfunction

Question 26

What enzymes does Amiodarone potentially inhibit?

Answer 26

P-GP

CYP

Question 27

What are the Class 4 anti-dysrhythmias?

Answer 27

NDHP CCBs

Question 28

Under what category does Adenosine fall?

Answer 28

“Other”

Question 29

Indications for Adenosine

Answer 29

SVT

Pharm stress testing

Question 30

Adenosine MOA

Answer 30

SVT: Slows conduction through AVN, interupting reentry cycle.

Stress test: Vasodilates healthy coronary arteries but not stenotic ones/

Question 31

Adenosine side effects

Answer 31

Flushing
bronchospasm
dyspnea

Question 32

Contraindications for Adenosine

Answer 32

High heart block
SSS
bradycardia
bronchoconstrictive disease

Question 33

What is adenosine specifically not indicated for?

Answer 33

A-fid/flutter

V-tach

Question 34

Cardiac glycoside

Answer 34

Digoxin

Question 35

Digoxin MOA

Answer 35

Inhibits Na/K ATPase, promoting Ca influx, increasing cardiac contractility. Supresses AVN, slowing conduction.

Question 36

Indications for Digoxin

Answer 36

Mild to moderate HF

A-fib rate control

Question 37

Side effects of Digoxin

Answer 37

SSS
Dig toxicity
Partial heart block becoming a complete heart block

Question 38

Contraindications for Digoxin

Answer 38

Thyroid d/o
Recent MI
V-fib (duh)

Question 39

What list does Digixin make?

Answer 39

BEERS

Question 40

MgSO4 MOA

Answer 40

Unknown

Question 41

Indications for MgSO4

Answer 41

Dig or low Mg induced VT/VF
(Torsades)
(Pre)eclampsia

Question 42

MgSO4 side effects

Answer 42

Flushing
HOTN
hyperMg++

Question 43

Contraindications for MgSO4

Answer 43

Heart block