Anti-histamine Drugs

Question 1

Cromolyn sodium

Answer 1

Mast cell stabilizer

Directly inhibits mast cell degranulation

Question 2

Diphenhydramine

Answer 2

First generation antihistamine
Benadryl
3+ anti Ach/sed
Anti motion and sleep aid

Question 3

Dimenhydrinate

Answer 3

First gen antihistamine
Dramamine
3+ Anti Ach/sed
Anti motion sickness

Question 4

Chlorpheniamine

Answer 4

First gen antihistamine
Less sedation
OTC cold meds

Question 5

Fexofenadine

Answer 5

Second gen antihistamine

Question 6

Loratidine

Answer 6

Second gen antihistamine

Question 7

Cetirizine

Answer 7

Second gen antihistamine

Question 8

What are antihistamines most useful for?

Answer 8

Allergic rhinitis
Allergic conjunctivitis
Urticaria

Question 9

What are antihistamines not useful for?

Answer 9

Anaphylaxis

Common cold

Question 10

Action of H1 antihistamines

Answer 10

Inverse agonist at H1 receptors on smooth muscle, endothelium, and brain

Question 11

H1 Antagonist 1st generation drugs

Answer 11

Diphenhydramine (Benadryl)
Dimenhydrinate (Dramamine)
Chlorpheniramine

Question 12

H1 Antagonist drugs, 2nd generation

Answer 12

Loratidiine
Cetrizine
Fexofenadine