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General Pharmacology for Bio Exam > Anti-emetics > Flashcards

Anti-emetics Flashcards

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Biology 101 flashcards
1
Q

Indications for H1 receptor antagonists?

A

Motion sickness

Morning sickness

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2
Q

Contra-indications for H1 receptor antagonists?

A

Avoid Cyclazine in acute porphyrias

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3
Q

Common side effects of H1 receptor antagonists?

A

Drowsiness

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4
Q

Can all anti-emetics be abruptly stopped?

A

Yes

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5
Q

Indications for Dopamine antagonists?

A

Chemotherapy induced N&V

PONV

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6
Q

What type of medication is Metoclopromide?

A

Dopamine antagonist

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7
Q

What are the contra-indications for Metoclopromide?

A

3-4 days post GI surgery
GI haemorrhage/obstruction/perforation
Phaeochromocytoma

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8
Q

What are side effects of Metoclopromide?

A 
EPS
Galactorrhoea
Gynaecomastia
Hyperprolactinaemia
Menstrual changes
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9
Q

What type of medication is Domperidone?

A

Dopamine Antagonist

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10
Q

What are contra-indications for Domperidone?

A

Cardiac Disease
Conditions where cardiac conduction is/will be impaired
Where increased GI motility is harmful
Prolactinoma

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11
Q

Common side effects of Domperidone

A

Drowsiness
Dry mouth
Malaise

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12
Q

Indications of 5HT3 Receptor antagonists

A

Chemo induced N&V

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13
Q

Contra-indications for 5HT3 receptor antagonists

A

Congenital long QT syndrome (Ondansetron)

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14
Q

Common side effects of 5HT3 Receptor antagonists?

A 
Constipation
Headache
Diarrhoea (Granisetron/Palanosetron)
Insomnia (Granisetron)
Flushing (Ondansetron)
Injection side reactions (Ondansetron)
Dizziness (Palanosetron)
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15
Q

Side effects of Droperidol?

A

Drowsiness

Hypotension

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16
Q

Contra-indications of Droperidol?

A 
Bradycardia; 
CNS depression; 
comatose states; 
hypokalaemia; 
hypomagnesaemia; 
phaeochromocytoma; 
QT-interval prolongation

General Pharmacology for Bio Exam (15 decks)

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