Anti-emetics Flashcards

1
Q

Serotonin Blockers

ondansetron (zofran)
dolasetron

SUBLINGUAL OR IV

A

Use: Tx N/V in chemo pt (30-3 hrs before treatment)

SE: H/A, dizzy, diarrhea

Nurse: IV OR SUBLING BEFORE CHEMO

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2
Q

Substance P/Neurokinin

aprepitant (Emend)

A

Use: combo therapy with steroids or ondansetron
SE: fatigue, diarrhea, dizzy
Watch: children and liver/ kidney

Used post-op N/V and CINV

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3
Q

Dopamine Antagonist

prochlorperazine
promethazine

A

Use: emesis d/t chemo, opioids, post-op

SE: EPS (restless, anxiety, muscle spasm = give lorazepam or Benadryl)
Hypotension, anticholinergic, sedation

Watch: children/elderly, pt with urinary retention, asthma, narrow glaucoma

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4
Q

Metoclopramide

“Stimulates peristalsis”

A

Use: post-op, GERD, delayed emptying

SE: EPS, sedation, diarrhea
Watch: GI, seizures, children/elderly

Med: other sedatives, CNS depression, opioids

Nurse: monitor EPS, CNS depression

<10 mg = undiluted over 2 min
> 10 mg = dilute D5W or LR over 15 min

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5
Q

Steroid

dexamethasone

A

Use: combo with other meds to decrease CINV

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6
Q

Cannabinoid

dronabinal

A

Use: CINV
SE: risk for depression/anxiety

NO TO PSYCH PATIENTS

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7
Q

Anticholinergic

scopolamine (Transderm-Scop) PATCH

A

Use: motion sickness (boats), pt with increased N/V with anesthesia

SE: sedation, anticholinergic effect

Watch: pt with renal, asthma, narrow glaucoma

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8
Q

Antihistamine

diphenhydrinate (Dramamine)

A

Use: motion sickness
SE: sedation, anticholinergic

Med: CNS depression, HTN meds, anticholinergics

Nurse: use in combo to decrease SE. PROPHYLACTICALLY

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