Anti-diarrheals

Question 1

diphenoxylate

loperamide

Answer 1

Use: decrease stool frequency and content

Watch: IBD (megacolon)
Med: increase levels = opioid effects CNS increase

Nurse: I&O before, during, and after. Watch dehydration

Question 2

Increase intentional flora

L. acidophilus

Answer 2

Use: prevent/stop diarrhea

Nurse: I&O before, during, and after. Watch dehydration. Hx of bowels

Also use:

psyllium (bulk)
laculose (ph- ammonia)
SE: gas, burp, diarrhea

Question 3

IBS with diarrhea (> 6 months)

aosetron

Answer 3

Use: IBS with diarrhea

SE: constipation, bowel obstruction

Nurse: I&O before, during, and after. Watch dehydration

Question 4

IBS with constipation

lubiprostone

Answer 4

Use: increase fluid = increase motility

FOR IBS WITH CONSTIPATION

SE: diarrhea/N/V (take with food)

Question 5

5- Aminosalicylates

sulfasalazine

Answer 5

Use: decrease inflammation in IBS, Crohn’s, UC

SE: blood problems, nausea, cramps, rash