Anti-Effectives

Question 1

Drug of choice for pregnant women with a bacterial infection.

Answer 1

Tobramycin - (Tobrex or TobraDEX)

Question 2

Aminoglycoside used for severe eye infections and cannot use while operating heavy machinery

Answer 2

Gentamycin

Question 3

Major side effect of Gentamycin and causes increase of the intragranial pressure

Answer 3

Pseudotumor cerebri

Question 4

Aminoglycosides cause weakness in what type of autoimmune neuromuscular disorder

Answer 4

Myasthenia Gravis

Question 5

What type of hypersensitivity is related to Neomycin usage?

Answer 5

Type 4

Question 6

What 2 drugs inactivate Aminoglycosides?

Answer 6

Penicillins and Cephlasporins

Question 7

What is the best pregnant drug used for Blepharitis?

Answer 7

Azithromycin (Best used for Preg B)

Question 8

What type of drug will increase levels of Theophylline?

Answer 8

Macrolides

Note: Rise in Theophylline will increase metabolism

Question 9

What bacteriostatic drug will cause grey baby syndrome?

Answer 9

Chloramphenicol

Note: Bacteriostatic

Question 10

Which drug type becomes more Gram + as new generations get created?

Answer 10

Fluoroquinolones

Question 11

What type of FQ is great for Bacterial Keratitis?

Answer 11

Levofloxacin

Question 12

What is the best type of FQ to use on Paediatric infections?

Answer 12

Moxifloxacin

Question 13

What type of FQ causes white corneal precipitates?

Answer 13

Ciprofloxacin

Question 14

What type of drug inhibits Dihydropteroate synthase?

Answer 14

Sulfonamides - acts as a competitive antagonist

Question 15

What drug inhibits Dihydrofolate reductase and doesn’t aloow THF to be created?

Answer 15

Trimethoprine or Pyrimethamine

Question 16

What drug is the first line of defense against MRSA?

Answer 16

Trimethoprine

Question 17

True or False. Sulfonamides are structural analogs of Maba?

Answer 17

False. They are analogs of PABA

Question 18

What combo drug is used to treat taxoplasmosis?

Answer 18

Sulfadiazine and Pyrimethamine

Question 19

What type of drug has an adverse effect which causes myopia?

Answer 19

Sulfonamides

Question 20

What do you not ingest when taking a TC?

Answer 20

Milk or Anti - acid

Divalent cation binding will occur

Question 21

What drug is associated with infants developing poor teeth?

Answer 21

Doxycycline

Used for: MAC
Meibianitis/Meibomian Gland Stasis
Acne Roseca
Chlamydia

Question 22

What are TC used for primarily in Optometric setting?

Answer 22

Lid Infections

Question 23

If a pt. has a lung problem, what is the best anti-inflammatory drug for this use?

Answer 23

Tetracycline

Question 24

What drug type causes increased warfarin effect and anti coagulation?

Answer 24

Tetracycline

Question 25

What is very common adverse reaction in children?

Answer 25

Pseudotumor Cerebri - Increased intercranial pressure

Question 26

What is the best drug to use for children with acute bacterial infection?

Answer 26

Polymixin B and Trimethoprim

Question 27

What type toxicity could Polymixin B generate?

Answer 27

Nephrotoxicity

Question 28

What are 4 main type of anti effectives that are GM - ?

Answer 28

PAFT Polymixin B AG's FQ TC

Question 29

What are the 2 dose dependent drugs?

Answer 29

AG and FQ

Question 30

MRSA is resistant to what PCN the most?

Answer 30

Methicillin

Question 31

What type of drug has an adverse rxn to Vit K and Hemophilia?

Answer 31

Cephalosporins Note: Destroy's intestinal microflora

Question 32

Why is Bacitracin not used orally?

Answer 32

Due to Nephrotoxicity

Question 33

What drug causes Red Man syndrome?

Answer 33

Vancomycin

Question 34

When should you use a steroid?

Answer 34

When you see inflammation near the limbus

Question 35

In regards to drug resistance, what type of drugs should be selected?

Answer 35

Narrow spectrum and Older agents

Question 36

What is the most common cold virus influenced by an eye infection?

Answer 36

Adenovirus

Question 37

What type of drug fo you not give Herpes pts.'s?

Answer 37

Steroids

Question 38

What is the first line of therapy for HSV1 and HSV2 Keratitis?

Answer 38

Trifluridine (Pyrimidine)

Question 39

What is the anti viral drug of choice for Cytomegalovirus?

Answer 39

Acyclovir

Question 40

What drug is used for acutre herpetic keratitis?

Answer 40

Ganciclovir

Question 41

What is the only antifungal used by Optometrists?

Answer 41

Natamycin

Question 42

What type of antifungal impairs cyp450?

Answer 42

Azole

Question 43

What is the main adverse rxn of Azoles?

Answer 43

Hepatotoxicity Use Echinocandins

Question 44

What is the great imposter?

Answer 44

Acanthamoeba Use: Bigunaides